A New Method for Screening of Hyperammonemia

  • K. Tada
  • H. Tateda
  • K. Metoki
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 153)

Abstract

A number of enzymatic defects are known such as congenital hyperammonemia, citrullinemia, argininosuccinic aciduria or hyperargininemia, which involve the urea cycle. Patients with these disorders exhibit mental retardation, presumably resulting from intoxication with ammonia. Mental retardation can be prevented by early treatment with a low protein diet and/or use of sodium benzoate to decrease the blood ammonia level.

Keywords

Urea Cycle Sodium Benzoate Perinatal Asphyxia Blood Ammonia Ornithine Transcarbamylase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • K. Tada
    • 1
  • H. Tateda
    • 1
  • K. Metoki
    • 1
  1. 1.Department of PediatricsTohoku University Medical SchoolSendai 980Japan

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