Xeno-Transplantation and Xenozoonoses

  • E. Joost Ruitenberg
Part of the Developments in Hematology and Immunology book series (DIHI, volume 37)


Transplantation of organs such as hearts or kidneys from one individual to another has become a highly successful mode of therapy. According to reports of the FDA (US Food and Drug Administration) and CBER (Center for Biologics Evaluation and Research) in the US ten patients die every day in the US, because a needed organ is not available to them. The supply of organs in the US is based on about 5.000 donors annually. The demands, however, rose from about 20.000 in 1990 to more than 60.000 patients waiting for organs in 1998. These huge needs stimulated research on xenografts as donor organs.


Hyperacute Rejection Marburg Virus Endogenous Type Human Kidney Cell Line Primary Peripheral Blood Mononuclear Cell 
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Copyright information

© Springer Science+Business Media Dordrecht 2002

Authors and Affiliations

  • E. Joost Ruitenberg
    • 1
    • 2
    • 3
  1. 1.CLB-SanquinAmsterdamNL
  2. 2.Department Biology and SocietyFree UniversityAmsterdamNL
  3. 3.Department of Immunology, Fac. Veterinary MedicineUniversity of UtrechtNL

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