Use of the Albumin/Creatinine Ratio in Patient Care and Clinical Studies

  • James H. Warram
  • Andrzej S. Krolewski


In patients with diabetes, elevated urinary albumin excretion (UAE) indicates the existence of functional as well as morphological abnormalities in the kidney [1–3]. Therefore, measurement of UAE is used for the early diagnosis of diabetic kidney disease as well as for monitoring its natural course and the effectiveness of treatment. Quantitative and semiquantitative methods are used to measure UAE.


Diabetic Nephropathy Cumulative Incidence Diabetic Kidney Disease IDDM Patient Albumin Creatinine Ratio 
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Copyright information

© Springer Science+Business Media Dordrecht 1998

Authors and Affiliations

  • James H. Warram
    • 1
  • Andrzej S. Krolewski
    • 1
  1. 1.Section on Genetics and Epidemiology Joslin Diabetes CenterBostonUSA

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