Diabetes, Hypertension, and Kidney Disease in the Pima Indians

  • William C. Knowler
  • Robert G. Nelson
  • David J. Pettitt


Hypertension and kidney disease are well-known concomitants of both type 1 and type 2 diabetes mellitus. Hypertension, kidney disease, and diabetes are associated with each other, but the associations vary between populations, and the causal interpretations, especially regarding hypertension and diabetic nephropathy, are controversial. The complications of diabetes have been studied extensively among the Pima Indians of Arizona, U.S.A. In this chapter, we describe the epidemiology of diabetic renal disease and its relationship with hypertension in the Pima Indians.


Glomerular Filtration Rate Diabetic Nephropathy High Blood Pressure Impaired Glucose Tolerance Normal Glucose Tolerance 
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Copyright information

© Springer Science+Business Media Dordrecht 1998

Authors and Affiliations

  • William C. Knowler
    • 1
  • Robert G. Nelson
    • 1
  • David J. Pettitt
    • 1
  1. 1.National Institute of Diabetes and Digestive and Kidney DiseasesPhoenixUSA

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