Diabetes, Hypertension, and Kidney Disease in the Pima Indians

  • William C. Knowler
  • Robert G. Nelson
  • David J. Pettitt


Hypertension and kidney disease are well-known concomitants of both insulin-dependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus (NIDDM). Hypertension, kidney disease, and diabetes are associated with each other, but the nature of the associations varies between populations, and the causal interpretations, especially regarding hypertension and diabetic nephropathy, are controversial. The complications of diabetes have been studied extensively among the Pima Indians of Arizona, U.S.A. In this chapter, we describe the epidemiology of diabetic renal disease and its relationship with hypertension in the Pima Indians.


Kidney Disease Diabetic Nephropathy Impaired Glucose Tolerance Normal Glucose Tolerance Urinary Albumin Excretion 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • William C. Knowler
    • 1
  • Robert G. Nelson
    • 1
  • David J. Pettitt
    • 1
  1. 1.Department of Healthy & Human ServicesNational Institutes of HealthPhoenixUSA

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