Diabetes, Hypertension, and Kidney Disease in the Pima Indians Compared with Other Populations

  • William C. Knowler
  • Robert G. Nelson
  • David J. Pettitt


Hypertension and kidney disease are well-known concomitants of both insulindependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus (NIDDM). Hypertension, kidney disease, and diabetes are associated with each other, but the nature of the associations varies between populations, and the causal interpretations, especially regarding hypertension and diabetic nephropathy, are controversial. The complications of diabetes have been studied extensively among the Pima Indians of Arizona, U.S.A. In this chapter, we describe the epidemiology of diabetic renal disease and its relationship with hypertension in the Pima Indians in comparison with other populations.


Glucose Tolerance Diabetic Nephropathy Impaired Glucose Tolerance Normal Glucose Tolerance Dependent Diabetes Mellitus 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • William C. Knowler
  • Robert G. Nelson
  • David J. Pettitt

There are no affiliations available

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