Adaptive Properties of Monoaminergic Neurons

  • Michael J. Zigmond
  • Edward M. Stricker


Neural systems often serve to transmit information rapidly from one region to another. As such, they are highly responsive to alterations in input, quickly translating these signals into isomorphic changes in distal targets. This is the way in which primary sensory afferent and skeletal motor efferent pathways operate. The prototypical synapse for such systems is the mammalian neuromuscular junction. Here, acetylcholine produces a rapid but transient alteration of membrane conductance, thereby generating a postsynaptic potential of millisecond duration. Transmission at these synapses can operate over a wide range of frequencies and for extended periods of time.


Tyrosine Hydroxylase Transmitter Release Monoaminergic System Adaptive Property Tyrosine Hydroxylase Activity 
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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Michael J. Zigmond
    • 1
  • Edward M. Stricker
    • 2
  1. 1.Department of Biological SciencesUniversity of PittsburghPittsburghUSA
  2. 2.Department of PsychologyUniversity of PittsburghPittsburghUSA

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