Abstract
A solution of 174 g (about 1 mole) of methyl 5-(chloromethyl)-2-furoate (see Vol. 1 of this work, p. 29), b.p. 114–116°/3 mm, in 400 ml of methanol was prepared in a one-liter three-necked round-bottomed flask fitted with mercury-sealed stirrer, dropping funnel, and thermometer. The solution was stirred while a solution of 100 g (about 1.5 moles) of technical potassium cyanide in 200 ml of water was added rapidly; the temperature of the mixture then rose to 25–30°. The mixture was then heated in a water bath to 30–35°, and the temperature was kept in this range while stirring was continued for six hours.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literature Cited
O. Moldenhauer, G. Trautmann, W. Irion, R. Pfluger, H. Doser, D. Mastaglio, H. Marwitz, and R. Schulte, A. 580, 169 (1953).
Editor information
Rights and permissions
Copyright information
© 1959 Springer Science+Business Media New York
About this chapter
Cite this chapter
Mndzhoian, A.L. (1959). Methyl 5-(Cyanomethyl)-2-Furoate. In: Mndzhoian, A.L. (eds) Syntheses of Heterocyclic Compounds. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6658-5_46
Download citation
DOI: https://doi.org/10.1007/978-1-4757-6658-5_46
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-6660-8
Online ISBN: 978-1-4757-6658-5
eBook Packages: Springer Book Archive