The reaction was carried out in a 100-ml round-bottomed flask fitted with reflux condenser protected by a calcium chloride tube. In order to trap the hydrogen chloride and sulfur dioxide formed in the reaction the end of the calcium chloride tube was connected to a Tishchenko vessel containing a solution of caustic alkali. A solution of 12.6 g (0.1 mole) of 5-methy1–2-furoic acid (see p. 23), m.p. 108–109°, in 40 ml of dry benzene was introduced into the flask, and a solution of 13.1 g (0.11 mole) of freshly distilled thionyl chloride in 30 ml of dry benzene was added.
KeywordsWater Bath Calcium Chloride Sulfur Dioxide Heterocyclic Compound Acid Chloride
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