Methyl 5-(Chloromethyl)-2-Furoate

  • A. L. Mndzhoian

Abstract

A mixture of 126 g (1 mole) of methyl 2-furoate (see p. 27), b.p. 180–181°/760 mm, 250 ml of dry dichloroethane (Note 1), 45 g of paraformaldehyde (1.5 moles calculated as formaldehyde), and 34 g (0.25 mole) of anhydrous zinc chloride was prepared in a one-liter four-necked round-bottomed flask fitted with stirrer, bent tube reaching to the bottom of the flask, thermometer, and gas-outlet tube. A rapid stream of hydrogen chloride was passed first through a wash bottle containing sulfuric acid and then into the stirred mixture. The temperature of the reaction mixture gradually rose; in order to avoid resinification, the flask was cooled with water so as to prevent the temperature from rising above 24–26°. The reaction lasted about two hours; the end of the reaction was indicated by the complete dissolution of the para-formaldehyde: the spontaneous evolution of heat gradually stopped, and the mixture became light yellow in color.

Keywords

Carbon Tetrachloride Aluminum Chloride Hydrogen Chloride Stannic Chloride Chloride Hexahydrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1959

Authors and Affiliations

  • A. L. Mndzhoian

There are no affiliations available

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