Abstract
Rhabdomyolysis is defined as disintegration or dissolution of striped muscle and, regardless of the etiology, results in myocyte death with the release of myoglobin into the systemic circulation. Accounts of rhabdomyolysis can be found as far back as the Old Testament, but Bywaters and Beall first associated crush injuries with dark urine, shock, and renal failure in patients who were bombing casualties during World War II (1). Since that time, rhabdomyolysis has become recognized as one of the most common causes of acute renal failure (ARF) in the United States, with the estimated risk of ARF following rhabdomyolysis ranging from 4% to 33% (2–4).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bywaters EG, Beall D. Crush injuries with impairment of renal function. Br Med J 1941; 1: 427–35.
Slater MS, Mullins RJ. Rhabdomyolysis and myoglobinuric renal failure in trauma and surgical patients: a review. J Am Coll Surg 1998; 186: 693–716.
Ron D, Taitelman U, Michaelson M, Bar-Joseph G, Bursztein S, Better OS. Prevention of acute renal failure in traumatic rhabdomyolysis. Arch Intern Med 1984; 144: 277–80.
Better OS, Stein RI. Early management of shock and prophylaxis of acute renal failure in traumatic rhabdomyolysis. N Engl J Med 1990; 322: 825–9.
Knochel JP. Serum calcium derangements in rhabdomyolysis. N Engl J Med 1981; 305: 161–3.
Guharay F, Sachs F. Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle. J Physiol 1984; 352: 685–701.
Knochel JP, Rhabdomyolysis and myoglobinuria. Annu Rev Med 1982; 33: 435–43.
Reis ND, Michaelson M. Crush Injury to the Lower Limbs. Treatment of the local injury. J Bone Joint Surg Am 1986; 68: 414–8.
Boles JM. Rhabdomyolysis and compartment syndrome In: Webb AR, Shapiro MJ, Singer M, Suter PM (eds). Oxford Textbook of Critical Care, Oxford, Oxford University Press, 1999, 722725.
Eneas JF, Schoenfeld PY, Humphreys MH. The effect of infusion of mannitol-sodium bicarbonate on the clinical course of myoglobinuria. Arch Intern Med 1979; 139: 801–5.
Meroney WH, Amey GK, Seger WE, Balch HH. The acute calcification of traumatized muscle, with particular reference to acute post-traumatic renal insufficiency. J Clin Invest 1957; 36: 825–32.
Cheung JY, Bonventre JV, Malis CD, Leaf A. Calcium and ischemic injury. N Engl J Med 1986; 314: 1670–6.
Knochel JP. Serum calcium derangements in rhabdomyolysis. N Engl J Med 1981; 305: 161–3.
Visweswaran P, Guntupalli J, Rhabdomyolysis. Crit Care Clin 1999; 15: 415–28.
Yuile CL, Gold MA, Hinds EG. Hemoglobin precipitation in renal tubules; a study of its causes and effects. J Exp Med 1945; 82: 361–74.
Perri GC, Gorini P. Uraemia in the rabbit after injection of crystalline myoglobin. Br J Exp Pathol 1952; 33: 440–4.
Ward MM. Factors predictive of acute renal failure in rhabdomyolysis. Arch Intern Med 1988; 148: 1553–7.
Knottenbelt JD. Traumatic rhabdomyolysis from severe beating–experience of volume diuresis in 200 Patients. J Trauma 1994; 37: 214–9.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Springer Science+Business Media New York
About this chapter
Cite this chapter
Tull, F., Borrelli, J. (2001). Rhabdomyolysis. In: O’Donnell, J.M., Nácul, F.E. (eds) Surgical Intensive Care Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6645-5_46
Download citation
DOI: https://doi.org/10.1007/978-1-4757-6645-5_46
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-6647-9
Online ISBN: 978-1-4757-6645-5
eBook Packages: Springer Book Archive