Skip to main content

Postoperative Myocardial Infarction

  • Chapter
Surgical Intensive Care Medicine

Abstract

Postoperative myocardial infarction (PMI) was first described in 1952 (1). Approximately 7 to 8 million noncardiac surgical patients are at risk for cardiac morbidity or mortality annually (2). The reported incidence of PMI in the literature varies between 0.0 and 0.7% (2) and is as high as 37% in patients who have surgery within 3 months of a myocardial infarction (MI) (3). Approximately 50,000 patients annually have a PMI and 20,000 are fatal (2). There is now a better understanding of the factors that lead to the development of PMI, but many areas of controversy remain. The relationship between perioperative ischemia and PMI is uncertain. The factors leading to PMI in a cardiac surgical population may be different from the non-cardiac group, and within the non-cardiac group there appear to be varying degrees of risk depending on many factors, including the type of surgical procedure (3–10). One undisputed fact is the existence of certain patient populations at increased risk of PMI (11). The following discussion focuses predominantly on PMI in the non-cardiac surgical population.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Wroblewski F, LaDue JS. Myocardial infarction as a postoperative complication of major surgery. JAMA 1952; 150: 1212–6.

    Article  CAS  Google Scholar 

  2. Mangano DT. Perioperative cardiac morbidity. Anesthesiology 1990; 72: 153–84.

    Article  PubMed  CAS  Google Scholar 

  3. Tarhan S, Moffitt EA, Taylor WF, Giuliani ER. Myocardial infarction after general anesthesia. JAMA 1972;: 220: 1451–4.

    Google Scholar 

  4. Goldman L, Caldera DL, Nussbaum SR, Southwick FS, Krogstad D, Murray B, Burke DS, O’Malley TA, Goroll AH, Caplan CH, Nolan J, Carabello B, Slater EE. Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med 1977; 297: 845–50.

    Article  PubMed  CAS  Google Scholar 

  5. Ashton CM, Petersen NJ, Wray NP, Kiefe CI, Dunn JK, Wu L, Thomas JM. The incidence of perioperative myocardial infarction in men undergoing noncardiac surgery. Ann Intern Med 1993; 118: 504–10.

    PubMed  CAS  Google Scholar 

  6. Eagle KA, Coley CM, Newell JB, Brewster DC, Darling RC, Strauss 11W, Guiney TE, Boucher CA. Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery. Ann Intern Med 1989; 110: 859–66.

    PubMed  CAS  Google Scholar 

  7. Detsky AS, Abrams HB, McLaughlin JR, Drucker DJ, Sasson Z, Johnston N, Scott JG, Forbath N, Hilliard JR. Predicting cardiac complications in patients undergoing non-cardiac surgery. J Gen Intern Med 1986; 1: 211–9.

    Article  PubMed  CAS  Google Scholar 

  8. Steen PA, Tinker JH, Tarhan S. Myocardial reinfarction after anesthesia and surgery. JAMA 1978; 239: 2566–70.

    Article  PubMed  CAS  Google Scholar 

  9. Rao TL, Jacobs KH, EI-Etr AA. Reinfarction following anesthesia in patients with myocardial infarction. Anesthesiology 1983; 59: 499–505.

    Google Scholar 

  10. Hertzer NR. Fatal myocardial infarction following peripheral vascular operations. A study of 951 patients followed 6 to 11 years postoperatively. Cleve Clin Q 1982; 49: 1–11.

    PubMed  CAS  Google Scholar 

  11. Hertzer NR. Basic data concerning associated coronary disease in peripheral vascular patients. Ann Vasc Surg. 1987; 1: 616–20.

    Article  PubMed  CAS  Google Scholar 

  12. Nelson AH, Fleisher LA, Rosenbaum SH. Relationship between postoperative anemia and cardiac morbidity in high-risk vascular patients in the intensive care unit. Crit Care Med 1993; 21: 860–6.

    Article  PubMed  CAS  Google Scholar 

  13. Chapman I. Morphogenesis of occluding coronary artery thrombosis. Arch Pathol 1965; 80: 256–61.

    PubMed  CAS  Google Scholar 

  14. Constantinides P. Plaque fissures in human coronary thrombosis. J Atheroscler Res 1966; 6: 1–17.

    Article  Google Scholar 

  15. Kawai C. Pathogenesis of acute myocardial infarction. Novel regulatory systems of bioactive substances in the vessel wall. Circulation 1994; 90: 1033–43.

    Article  PubMed  CAS  Google Scholar 

  16. Slogoff S, Keats AS. Does perioperative myocardial ischemia lead to postoperative myocardial infarction? Anesthesiology 1985; 62: 107–14.

    Article  PubMed  CAS  Google Scholar 

  17. Badner NH, Knill RL, Brown JE, Novick TV, Gelb AW. Myocardial infarction after noncardiac surgery. Anesthesiology 1998; 88: 572–8.

    Article  PubMed  CAS  Google Scholar 

  18. Latham P, Joshi GP. Coronary revascularization without cardiopulmonary bypass: use of ischemic preconditioning and adenosine. Anesthesiology 1998; 88: 828–30.

    Article  PubMed  CAS  Google Scholar 

  19. Stanley GD, Pierce ET, Moore WJ, Lewis KP, Bode RH Jr. Spinal anesthesia reduces oxygen consumption in diabetic patients prior to peripheral vascular surgery. Reg Anesth 1997; 22: 53–8.

    Article  PubMed  CAS  Google Scholar 

  20. Westenskow DR, Jordan WS. Changes in oxygen consumption induced by fentanyl and thiopentone during balanced anaesthesia. Can Anaesth Soc J 1978; 25: 18–21.

    Article  PubMed  CAS  Google Scholar 

  21. Waxman K, Lazrove S, Shoemaker WC. Physiologic responses to operation in high risk surgical patients. Surg Gynecol Obstet 1981; 152: 633–8.

    PubMed  CAS  Google Scholar 

  22. Weissman C. The metabolic response to stress: an overview and update. Anesthesiology 1990; 73: 308–27.

    Article  PubMed  CAS  Google Scholar 

  23. Halter JB, Pflug AE, Porte D Jr. Mechanisms of plasma catecholamine increase during surgical stress in man. J Clin Endocrinol Metab. 1977; 45: 936–44.

    Article  PubMed  CAS  Google Scholar 

  24. Collins GJ Jr, Barber JA, Zajtchuk R, Vanek D, Malogne LA. The effects of operative stress on the coagulation profile. Am J Surg 1977; 133: 612–6.

    Article  PubMed  Google Scholar 

  25. Seyfer AE, Seaber AV, Dombrose FA, Urbaniak JRU. Coagulation changes in elective surgery and trauma. Ann Surg 1981; 193: 210–3.

    Article  PubMed  CAS  Google Scholar 

  26. McDaniel MD, Pearce WH, Yao JS, Rossi EC, Fahey VA, Green D, Flinn WR, Bergan JJ. Sequential changes in coagulation and platelet function following femorotibial bypass. J Vasc Surg 1984; 1: 261–8.

    PubMed  CAS  Google Scholar 

  27. Reeder MK, Muir AD, Foex P, Goldman MD, Loh L, Smart D. Postoperative myocardial ischaemia: temporal association with nocturnal hypoxaemia. Br J Anaesth 1991; 67: 626–31.

    Article  PubMed  CAS  Google Scholar 

  28. Reeder MK; Goldman MD; Loh L; Muir AD; Foex P; Casey KR; McKenzie PJ. Postoperative hypoxaemia after major abdominal vascular surgery. Br J Anaesth 1992; 68: 23–6.

    Article  PubMed  CAS  Google Scholar 

  29. Gutstein DE, Fuster V. Pathophysiology and clinical significance of atherosclerotic plaque rupture. Cardiovasc Res 1999; 41: 323–33.

    Article  PubMed  CAS  Google Scholar 

  30. Ambrose JA, Weinrauch M. Thrombosis in ischemic heart disease. Arch Intern Med 1996; 156: 1382–94.

    Article  PubMed  CAS  Google Scholar 

  31. Tofler GH. Triggering and the pathophysiology of acute coronary syndromes. Am Heart J 1997; 134 (5 Pt 2): S55–61.

    Article  PubMed  CAS  Google Scholar 

  32. Farb A, Burke AP, Tang AL, Liang TY, Mannan P, Smialek J, Virmani R. Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death. Circulation 1996; 93: 1354–63.

    Article  PubMed  CAS  Google Scholar 

  33. Plutzky J. Atherosclerotic plaque rupture: emerging insights and opportunities. Am J Cardiol 1999; 84 (1 A): 15J - 20J.

    Article  PubMed  CAS  Google Scholar 

  34. Chapman I. The initiating cause of coronary artery thrombosis: an anatomic study. J Mt Sinai Hosp NY 1969; 36: 361–74.

    CAS  Google Scholar 

  35. Barger AC, Beeuwkes R 3d. Rupture of coronary vasa vasorum as a trigger of acute myocardial infarction. Am J Cardiol 1990; 66: 41G - 43G.

    Article  PubMed  CAS  Google Scholar 

  36. Barger AC, Beeuwkes R 3d, Lainey LL, Silverman KJ Hypothesis: vasa vasorum and neovascularization of human coronary arteries. A possible role in the pathophysiology of atherosclerosis. N Engl J Med 1984; 310 (3): 175–7.

    Article  PubMed  CAS  Google Scholar 

  37. Arbustini E, Morbini P, Bello BD, Prati F, Specchia G. From plaque biology to clinical setting. Am Heart J 1999; 138 (2 Pt 2): S55–60.

    Article  PubMed  CAS  Google Scholar 

  38. Gurfinkel E, Bozovich G, Daroca A, Beck E, Mautner B. Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS Pilot Study. ROXIS Study Group. Lancet 1997; 350: 404–7.

    CAS  Google Scholar 

  39. Raby KE, Barry J, Creager MA, Cook EF, Weisberg MC, Goldman L. Detection and significance of intraoperative and postoperative myocardial ischemia in peripheral vascular surgery. JAMA 1992; 268: 222–7.

    Article  PubMed  CAS  Google Scholar 

  40. Hertzer NR, Beven EG, Young JR, O’Hara PJ, Ruschhaupt WF 3d, Graor RA, Dewolfe VG, Maljovec LC. Coronary artery disease in peripheral vascular patients. A classification of 1000 coronary angiograms and results of surgical management. Ann Surg 1984; 199: 223–33.

    Article  PubMed  CAS  Google Scholar 

  41. Poldermans D. Arnese M, Fioretti PM, Salustri A, Boersma E. Thomson IR, Roelandt JR, van Urk H. Improved cardiac risk stratification in major vascular surgery with dobutamine-atropine stress echocardiography. J Am Coll Cardiol 1995; 26: 648–53.

    Article  PubMed  CAS  Google Scholar 

  42. Detsky AS, Abrams HB, Forbath N, Scott JG, Hilliard JR. Cardiac assessment for patients undergoing noncardiac surgery. A multifactorial clinical risk index. Arch Intern Med 1986; 146: 2131–4.

    Article  PubMed  CAS  Google Scholar 

  43. Landesberg G, Einav S, Christopherson R, Beattie C, Berlatzky Y, Rosenfeld B, Eidelman LA, Norris E, Anner H, Mosseri M, Cotev S, Luria MH. Perioperative ischemia and cardiac complications in major vascular surgery: importance of the preoperative twelve-lead electrocardiogram. J Vasc Surg 1997; 26: 570–8.

    Article  PubMed  CAS  Google Scholar 

  44. Carliner NH, Fisher ML, Plotnick GD, Moran GW, Kelemen MH, Gadacz TR, Peters RW. The preoperative electrocardiogram as an indicator of risk in major noncardiac surgery. Can J Cardiol 1986; 2: 134–7.

    PubMed  CAS  Google Scholar 

  45. Gage AA, Bhayana JN, Balu V, Hook N. Assessment of cardiac risk in surgical patients. Arch Surg 1977; 112: 1488–92.

    Article  PubMed  CAS  Google Scholar 

  46. Cutler BS, Wheeler HB, Paraskos JA, Cardullo PA. Applicability and interpretation of electrocardiographic stress testing in patients with peripheral vascular disease. Am J Surg 1981; 141: 501–6.

    Article  PubMed  CAS  Google Scholar 

  47. Carliner NH, Fisher ML, Plotnick GD, Garbart H, Rapoport A, Kelemen MH, Moran GW, Gadacz T, Peters RW. Routine preoperative exercise testing in patients undergoing major non-cardiac surgery. Am J Cardiol 1985; 56: 51–8.

    Article  PubMed  CAS  Google Scholar 

  48. Gianrossi R, Detrano R, Mulvihill D, Lehmann K, Dubach P, Colombo A, McArthur D, Froelicher V. Exercise-induced ST depression in the diagnosis of coronary artery disease. A meta-analysis. Circulation. 1989; 80: 87–98.

    Article  PubMed  CAS  Google Scholar 

  49. Raby KE, Goldman L, Creager MA, Cook EF, Weisberg MC, Whittemore AD, Selwyn AP Correlation between preoperative ischemia and major cardiac events after peripheral vascular surgery N Engl J Med 1989; 321: 1296–300.

    CAS  Google Scholar 

  50. Boucher CA, Brewster DC, Darling RC, Okada RD, Strauss HW, Pohost GM. Determination of cardiac risk by dipyridamole-thallium imaging before peripheral vascular surgery. N Engl J Med 1985; 312: 389–94.

    Article  PubMed  CAS  Google Scholar 

  51. Leppo J, Plaja J, Gionet M, Tumolo J, Paraskos JA, Cutler BS. Noninvasive evaluation of cardiac risk before elective vascular surgery. J Am Coll Cardiol 1987; 9: 269–76.

    Article  PubMed  CAS  Google Scholar 

  52. Lette J, Waters D, Lapointe 7, Gagnon A, Picard M, Cerino M, Kerouac M. Usefulness of the severity and extent of reversible perfusion defects during thallium-dipyridamole imaging for cardiac risk assessment before noncardiac surgery. Am J Cardiol 1989; 64: 276–81.

    Article  PubMed  CAS  Google Scholar 

  53. Levinson JR, Boucher CA, Coley CM, Guiney TE, Strauss HW, Eagle KA. Usefulness of semiquantitative analysis of dipyridamole-thallium-201 redistribution for improving risk stratification before vascular surgery. Am J Cardiol 1990; 66: 406–10.

    Article  PubMed  CAS  Google Scholar 

  54. McEnroe CS, O’Donnell RF Jr, Yeager A, Konstam M, Mackey WC. Comparison of ejection fraction and Goldman risk factor analysis of dipyridamole thallium 201 studies in the evaluation of cardiac morbidity after aortic aneurysm surgery. J Vasc Surg 1990; 11: 497–504.

    PubMed  CAS  Google Scholar 

  55. Stratmann HG, Younis LT, Wittry MD, Amato M, Mark AL, Miller DD. Dipyridamole technetium 99m sestamibi myocardial tomography for preoperative cardiac risk stratification before major or minor nonvascular surgery. Am Heart J 1996; 132: 536–41.

    Article  PubMed  CAS  Google Scholar 

  56. Shaw L, Miller DD, Kong BA, Hilton T, Stelken A, Stocke K, Chaitman BR. Determination of perioperative cardiac risk by adenosine thallium-201 myocardial imaging. Am Heart J 1992; 124: 861–9.

    Article  PubMed  CAS  Google Scholar 

  57. Martin TW, Seaworth JE, Johns JP, Pupa LE, Condos WR. Comparison of adenosine, dipyridamole, and dobutamine in stress echocardiography. Ann Intern Med 1992; 116: 190–6.

    PubMed  CAS  Google Scholar 

  58. Mangano DT, London MJ, Tubau JF, Browner WS, Hollenberg M, Krupski W, Layug EL, Massie B. Dipyridamole thallium-201 scintigraphy as a preoperative screening test. A reexamination of its predictive potential. Study of Perioperative Ischemia Research Group. Circulation 1991; 84: 493502.

    Google Scholar 

  59. Vanzetto G, Machecourt J, Blendea D, Fagret D, Borrel E, Magne JL, Gattaz F, Guidicelli H. Additive value of thallium single-photon emission computed tomography myocardial imaging for prediction of perioperative events in clinically selected high cardiac risk patients having abdominal aortic surgery. Am J Cardiol 1996; 77: 143–8.

    Article  PubMed  CAS  Google Scholar 

  60. Garber AM, Solomon NA. Cost-effectiveness of alternative test strategies for the diagnosis of coronary artery disease. Ann Intern Med 1999; 130: 719–28.

    PubMed  CAS  Google Scholar 

  61. Halm EA, Browner WS, Tubau JF, Tateo IM, Mangano DT. Echocardiography for assessing cardiac risk in patients having noncardiac surgery. Study of Perioperative Ischemia Research Group. Ann Intern Med 1996; 125: 433–41.

    PubMed  CAS  Google Scholar 

  62. Poldermans D, Fioretti PM, Forster T, Thomson IR, Boersma E, el-Said EM, du Bois NA, Roelandt JR, van Uric H. Dobutamine stress echocardiography for assessment of perioperative cardiac risk in patients undergoing major vascular surgery. Circulation 1993; 87: 1506–12.

    Article  PubMed  CAS  Google Scholar 

  63. Fletcher JP, Antico VF, Gruenewald S, Kershaw LZ. Risk of aortic aneurysm surgery as assessed by preoperative gated heart pool scan. Br J Surg 1989; 76: 26–8.

    Article  PubMed  CAS  Google Scholar 

  64. Mosley JG, Clarke JM, Ell PJ, Marston A. Assessment of myocardial function before aortic surgery by radionuclide angiocardiography. Br J Surg 1985; 72: 886–7.

    Article  PubMed  CAS  Google Scholar 

  65. Pasternack PF, Imparato AM, Riles TS, Baumann FG, Bear G, Lamparello PJ, Benjamin D, Sanger J, Kramer E. The value of the radionuclide angiogram in the prediction of perioperative myocardial infarction in patients undergoing lower extremity revascularization procedures. Circulation 1985; 72 (3 Pt 2): 1113–7.

    Google Scholar 

  66. Mantha S, Roizen MF, Barnard J, Thisted RA, Ellis JE, Foss J. Relative effectiveness of four preoperative tests for predicting adverse cardiac outcomes after vascular surgery: a meta-analysis. Anesth Analg 1994; 79: 422–33.

    Article  PubMed  CAS  Google Scholar 

  67. Eagle KA, Brundage BH, Chaitman BR, Ewy GA, Fleisher LA, Hertzer NR, Leppo JA, Ryan T, Schlant RC, Spencer WH 3rd, Spittell JA Jr, Twiss RD, Ritchie JL, Cheitlin MD, Gardner TJ, Garson A Jr, Lewis RP, Gibbons RJ, O’Rourke RA, Ryan TJ. Guidelines for perioperative cardiovascular evaluation for noncardiac surgery. Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Committee on Perioperative Cardiovascular Evaluation for Noncardiac Surgery. Circulation 1996; 93: 1278–317.

    PubMed  Google Scholar 

  68. Palda VA. Detsky AS. Perioperative assessment and management of risk from coronary artery disease. Ann Intern Med 1997; 127: 313–28.

    PubMed  CAS  Google Scholar 

  69. Practice guidelines for pulmonary artery catheterization. A report by the American Society of Anesthesiologists Task Force on Pulmonary Artery Catheterization. Anesthesiology 1993; 78: 380–94.

    Article  Google Scholar 

  70. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EI, Sugarbaker DJ, Donaldson MC, Poss R, Ho KK, Ludwig LE, Pedan A, Goldman L Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation 1999; 100: 1043–9.

    Article  PubMed  CAS  Google Scholar 

  71. Muir AD, Reeder MK, Foex P, Ormerod OJ, Sear JW, Johnston C. Preoperative silent myocardial ischaemia: incidence and predictors in a general surgical population. Br J Anaesth 1991; 67: 373–7.

    Article  PubMed  CAS  Google Scholar 

  72. Charlson ME, MacKenzie CR, Ales KL, Gold JP, Fairclough GF Jr, Shires GT. The post-operative electrocardiogram and creatine kinase: implications for diagnosis of myocardial infarction after non-cardiac surgery. J Clin Epidemiol I989; 42: 25–34.

    Google Scholar 

  73. Mangano DT, Browner WS, Hollenberg M, London MJ, Tubau JF, Tateo IM. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery. The Study of Perioperative Ischemia Research Group. N Engl J Med 1990; 323: 1781–8.

    Article  Google Scholar 

  74. Alpert JS, Chipkin SR, Aronin N. Diabetes mellitus and silent myocardial ischemia. Adv Cardiol 1990; 37: 297–303.

    PubMed  CAS  Google Scholar 

  75. Savage RM, Wagner GS, Ideker RE, Podolsky SA, Hackel DB. Correlation of postmortem anatomic findings with electrocardiographic changes in patients with myocardial infarction: retrospective study of patients with typical anterior and posterior infarcts. Circulation 1977; 55: 279–85.

    Article  PubMed  CAS  Google Scholar 

  76. Andersen PT, Moller-Petersen J, Klaerke A, Henneberg EW. Evaluation of the usefulness of enzymatic diagnosis of myocardial infarction in patients with acute arterial occlusion of the lower extremities. Acta Anaesthesiol Scand 1987; 31: 38–43.

    Article  PubMed  CAS  Google Scholar 

  77. Graeber GM, Clagett GP, Wolf RE, Cafferty PJ, Harmon JW, Rich NM. Alterations in serum creatine kinase and lactate dehydrogenase. Association with abdominal aortic surgery, myocardial infarction and bowel necrosis. Chest 1990; 97: 521–7.

    Article  PubMed  CAS  Google Scholar 

  78. Zimmerman J, Fromm R, Meyer D, Boudreaux A, Wun CC, Smalling R, Davis B, Habib G, Roberts R. Diagnostic marker cooperative study for the diagnosis of myocardial infarction. Circulation 1999; 99: 1671–7

    Article  PubMed  CAS  Google Scholar 

  79. Ryan TJ, Antman EM, Brooks NH, Califf RM, Hillis LD, Hiratzka LF, Rapaport E, Riegel B, Russell RO, Smith EE 3rd, Weaver WD, Gibbons RJ, Alpert JS, Eagle KA, Gardner TJ, Garson A Jr, Gregoratos G, Ryan Ti, Smith SC Jr. 1999 Update. ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol 1999; 34: 890–911.

    Article  Google Scholar 

  80. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet 1988; 2: 349–60.

    PubMed  Google Scholar 

  81. Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ Jr, Cuddy TE, Davis BR, Geltman EM, Goldman S, Fiaker GC, Klein M, Lamas GA, Packer M, Rouleau J, Rouleau JL, Rutherford J, Wertheimer JH, Hawkins CM. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992; 327: 669–77.

    Article  PubMed  CAS  Google Scholar 

  82. Pfeffer MA, Braunwald E Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation 1990; 81: 1161–72.

    Article  PubMed  CAS  Google Scholar 

  83. Ohman EM, George BS, White CJ, Kern MJ, Gurbel PA, Freedman RI, Lundergan C, Hartmann JR, Talley JD, Frey MJ, Taylor G, Leimberger JD, Owens PM, Lee KL, Stack RS, Califf RM. Use of aortic counterpulsation to improve sustained coronary artery patency during acute myocardial infarction. Results of a randomized trial. The Randomized IABP Study Group. Circulation 1994; 90: 792–9.

    Article  PubMed  CAS  Google Scholar 

  84. Berlauk JF, Abrams JH, Gilmour IJ, O’Connor SR, Knighton DR, Cerra FB. Preoperative optimization of cardiovascular hemodynamics improves outcome in peripheral vascular surgery. A prospective, randomized clinical trial. Ann Surg 1991; 214: 289–97.

    Article  PubMed  CAS  Google Scholar 

  85. Mangano DT, Layug EL, Wallace A, Tateo I. Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery. Multicenter Study of Perioperative Ischemia Research Grouop. N Engl J Med 1996; 335: 1713–20.

    Article  PubMed  CAS  Google Scholar 

  86. Wallace A, Layug B, Tateo I, Li J, Hollenberg M, Browner W, Miller D, Mangano DT. Prophylactic atenolol reduces postoperative myocardial ischemia. McSPI Research Group. Anesthesiology 1998; 88: 7–17.

    Article  PubMed  CAS  Google Scholar 

  87. Poldermans D, Boersma E, Bax JJ, Thomson IR, van de Ven LL, Blankensteijn JD, Baars HF, Yo TI, Trocino G, Vigna C, Roelandt JR, van Uric H. The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. N Engl J Med 1999; 341: 1789–94.

    Article  PubMed  CAS  Google Scholar 

  88. Raby KE, Broil SJ, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore AD. The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. Anesth Analg 1999; 88: 477–82.

    PubMed  CAS  Google Scholar 

  89. Blackburn H. Standardization of the exercise electrocardiogram: a systematic comparison of chest lead configurations employed for monitoring during exercise. In: Karvonen MJ, Barry Ai, eds. Physical activity and the heart. Springfield, IL: CC Thomas, 1967: 90.

    Google Scholar 

  90. Practice guidelines for perioperative transesophageal echocardiography. A report by the American Society of Anesthesiologists and the Society of Cardiovascular Anesthesiologists Task Force on Transesophageal Echocardiography. Anesthesiology 1996; 84: 986–1006.

    Article  Google Scholar 

  91. Dodds TM, Stone JG, Coromilas J, Weinberger M, Levy DG. Prophylactic nitroglycerin infusion during noncardiac surgery does not reduce perioperative ischemia. Anesth Analg 1993; 76 (4): 705–13.

    Article  PubMed  CAS  Google Scholar 

  92. Thomson IR, Mutch WA, Culligan JD. Failure of intravenous nitroglycerin to prevent intraoperative myocardial ischemia during fentanyl-pancuronium anesthesia. Anesthesiology 1984; 61: 385–93.

    Article  PubMed  CAS  Google Scholar 

  93. Gallagher JD, Moore RA, Jose AB, Botros SB, Clark DL. Prophylactic nitroglycerin infusions during coronary artery bypass surgery. Anesthesiology 1986; 64: 785–9.

    Article  PubMed  CAS  Google Scholar 

  94. Kersten JR, Gross GJ, Pagel PS, Warltier DC. Activation of adenosine triphosphate-regulated potassium channels: mediation of cellular and organ protection. Anesthesiology 1998; 88: 495–513.

    Article  PubMed  CAS  Google Scholar 

  95. Ross S; Foex P. Protective effects of anaesthetics in reversible and irreversible ischaemia- reperfusion injury. Br J Anaesth 1999; 82: 622–32.

    Article  PubMed  CAS  Google Scholar 

  96. Bode RH Jr, Lewis KP, Zarich SW, Pierce ET, Roberts M, Kowalchuk GJ, Satwicz PR, Gibbons GW, Hunter JA, Espanola CC. Cardiac outcome after peripheral vascular surgery. Comparison of general and regional anesthesia. Anesthesiology 1996; 84: 3–13.

    Article  PubMed  Google Scholar 

  97. Yeager MP, Glass DD, Neff RK, Brinck-Johnsen T. Epidural anesthesia and analgesia in high-risk surgical patients. Anesthesiology 1987; 66: 729–36.

    Article  PubMed  CAS  Google Scholar 

  98. Thompson JF, Mullee MA, Bell PR, Campbell WB, Chant AD, Darke SG, Jamieson CW, Murk J, Parvin SD, Perry M, Ruckley CV, Wolfe IN, Clyne CA. Intraoperative heparinisation, blood loss and myocardial infarction during aortic aneurysm surgery: a Joint Vascular Research Group study. Eur J Vasc Endovasc Surg 1996; 12: 86–90.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer Science+Business Media New York

About this chapter

Cite this chapter

Stanley, G.D., Sundarakumaran, R. (2001). Postoperative Myocardial Infarction. In: O’Donnell, J.M., Nácul, F.E. (eds) Surgical Intensive Care Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6645-5_17

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-6645-5_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-6647-9

  • Online ISBN: 978-1-4757-6645-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics