Neuromuscular Blocking Agents

  • Rafael A. Ortega
  • Rubén Azocar


Neuromuscular blocking agents perhaps have the most fascinating history among the drugs used in anesthesiology and intensive care. South American aborigines used curare for centuries to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle (1). These historical facts should serve to remind us that this group of drugs is lethal when misused and that while paralysis occurs, intellectual function remains intact.


Intensive Care Unit Patient Neuromuscular Blockade Neuromuscular Blocking Agent Status Asthmaticus Peripheral Nerve Stimulation 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Rafael A. Ortega
    • 1
  • Rubén Azocar
    • 1
  1. 1.Boston University Medical CenterBostonUSA

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