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Nephrolithiasis and Nephrocalcinosis

  • Joan H. Parks
  • Fredric L. Coe
Chapter

Abstract

From time to time in most people, the urine separates into a solid and liquid phase. Unlike birds, which regularly produce a semisolid urine, all mammals have renal tubules and urinary collecting systems whose lumens are narrow and easily obstructed. As long as the solid phase in urine consists of very tiny particles, 0.1 to 10 microns in diameter, phase separation is asymptomatic. Larger particles can block tubule lumens or may adhere to papillary surfaces. Once anchored, a particle can then grow until its dimensions become similar in magnitude to those of the urinary tract, i.e., millimeters to centimeters in diameter. Then it can cause clinical disease.

Keywords

Uric Acid Calcium Oxalate Stone Disease Renal Tubular Acidosis Calcium Stone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Joan H. Parks
    • 1
  • Fredric L. Coe
    • 2
  1. 1.Program in Nephrology Department of MedicineThe University of ChicagoChicagoUSA
  2. 2.Program in Nephrology, Department of MedicineThe University of ChicagoChicagoUSA

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