Peritonitis and Other Complications

  • Charles E. Halstenson
  • William F. Keane


Infection is the most frequent clinical complication in patients with end-stage renal disease maintained on peritoneal dialysis (1). These infections include bacterial and fungal peritonitis as well as exit-site and catheter tunnel infections. The incidence of peritonitis is 3 to 5 times higher in patients maintained on continuous ambulatory peritoneal dialysis (CAPD) than in those on intermittent peritoneal dialysis and contributes to the morbidity and mortality of patients receiving CAPD therapy (2). During the 1980s the incidence of peritonitis was about 1.3 episodes per patient per year (3). This rate has declined over time with the introduction of various types of disconnect systems (4). These disconnect systems have predominantly decreased the risk of peritonitis due to skin organisms, e.g., coagulase-negative staphylococcus. The Y set, an example of disconnect technology, has also been associated with a decrease in the peritonitis rate to 1 episode per 24–36 months (5,6).


Peritoneal Dialysis Continuous Ambulatory Peritoneal Dialysis Peritoneal Dialysis Patient Chronic Peritoneal Dialysis Peritonitis Rate 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Charles E. Halstenson
    • 1
  • William F. Keane
    • 2
  1. 1.The Drug Evaluation Unit, Hennepin County Medical CenterUniversity of Minnesota College of PharmacyMinneapolisUSA
  2. 2.The Drug Evaluation Unit, Department of Medicine, Hennepin County Medical CenterUniversity of Minnesota Medical SchoolMinneapolisUSA

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