Vesicoureteral Reflux and Reflux Nephropathy

  • Robert A. Weiss
  • Adrian Spitzer

Abstract

Primary vesicoureteral reflux (VUR) is caused by a congenitally short ureteral tunnel through the bladder submucosa, associated with lateral displacement of the ureteral orifice. As a result, the resistance generated by the collapse of the ureteral tunnel when the bladder pressure rises (micturition) is overcome, and the urine flows in a retrograde direction, towards the kidney. VUR is the most common abnormality observed in children with urinary tract infections (UTIs). The condition was found in 30% of schoolgirls with covert bacteriuria (1) and 33% of children with overt infection (2). In contrast to the preponderance of females in the UTI population beyond infancy, the sex distribution of VUR in neonates with prenatal dilatation of the urinary tract is 5:1 male to female (3).

Keywords

Vesicoureteral Reflux Renal Scarring Acute Pyelonephritis Reflux Nephropathy Ureteral Reimplantation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Robert A. Weiss
    • 1
  • Adrian Spitzer
    • 2
  1. 1.New York Medical CollegeValhallaUSA
  2. 2.Division of Pediatric NephrologyAlbert Einstein College of MedicineBronxUSA

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