Nephrotic Syndrome

  • Patrizia Passerini
  • Claudio Ponticelli


The nephrotic syndrome is a clinical condition characterized by heavy proteinuria, hypoalbuminemia, hyperlipidernia, and variable degrees of edema. With the exception of minimal-change nephropathy, most primary glomerular diseases associated with the nephrotic syndrome tend to progress to renal failure. It is possible that the massive proteinuria and the lipid disorders that accompany the nephrotic syndrome may contribute to the progression (16). However, independent of renal outcome, the nephrotic state can favor thrombotic complications (7–10) and cardiovascular disease (11–17). Thus, the clinical management of nephrotic patients should take into consideration both the supportive measures aimed at reducing proteinuria and preventing the extrarenal complications and the specific pharmacological approach to the underlying disease.


Nephrotic Syndrome Membranous Nephropathy Idiopathic Nephrotic Syndrome Minimal Change Nephrotic Syndrome Membranoproliferative Glomerulonephritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Patrizia Passerini
    • 1
  • Claudio Ponticelli
    • 1
  1. 1.Instituto di Ricovero e Cura a Carattere Scientifico, Divisione di Nefrologia e Dialisi-Pad. CroffOspedale Maggiore di MilanoMilanoItaly

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