Renal Tubular Acidosis

  • Bruce Kaplan
  • Daniel Batlle


The kidney has as one of its major responsibilities the excretion of the daily nonvolatile acid load. On a normal American diet, this amounts to about 1 mEq of nonvolatile acid per kilogram body weight. This acid is excreted in the form of titratable acids (e.g., H2PO4 ) and ammonium (NH4 +). Alkali is usually excreted in much smaller amounts in the form of bicarbonate and organic anions (citrate, etc.). Renal net acid excretion thus equals the sum of the excretion of ammonium plus titratable acid minus bicarbonate and other anions.


Renal Tubular Acidosis Ammonium Excretion Distal Nephron Urinary Acidification Distal Renal Tubular Acidosis 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Bruce Kaplan
    • 1
  • Daniel Batlle
    • 2
  1. 1.Fexas Health Science Centr & Housth Division of Benal Disease and Hypertension 6431 Faxnin M5B 4.148.The UniversityHousthUSA
  2. 2.Division of Nephrology and HypertensionNorthwestern University Medical SchoolChicagoUSA

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