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Metabolic Changes Following Splenic Transplantation in a Case of Gaucher’s Disease

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Sphingolipids, Sphingolipidoses and Allied Disorders

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 19))

Abstract

The fact that the highest activity of glucocerebrosidase is normally found in the spleen (2) has suggested the possibility of splenic transplantation as a means of enzyme replacement in Gaucher’s disease (1). Technically successful splenic homotransplantations have been reported by Starzl and co-workers in six patients with diseases other than lipidosis (3, 9).

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Authors and Affiliations

  1. Karolinska Institute and Royal Veterinary College, University of Gothenburg and University of Lund, Stockholm, Sweden

    Carl G. Groth, Rolf Blomstrand, Lars Hagenfeldt, Per-Arne Ockerman, Karin Samuelsson & Lars Svennerholm

Authors
  1. Carl G. Groth
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  2. Rolf Blomstrand
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  3. Lars Hagenfeldt
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  4. Per-Arne Ockerman
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  5. Karin Samuelsson
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  6. Lars Svennerholm
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Editor information

Editors and Affiliations

  1. Isaac Albert Research Institute of the Kingsbrook Jewish Medical Center and Department of Pathology, Downstate Medical Center, State University of New York, Brooklyn, New York, USA

    Bruno W. Volk

  2. Department of Pathology, Miriam Hospital and Brown University, Providence, Rhode Island, USA

    Stanley M. Aronson

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© 1972 Springer Science+Business Media New York

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Groth, C.G., Blomstrand, R., Hagenfeldt, L., Ockerman, PA., Samuelsson, K., Svennerholm, L. (1972). Metabolic Changes Following Splenic Transplantation in a Case of Gaucher’s Disease. In: Volk, B.W., Aronson, S.M. (eds) Sphingolipids, Sphingolipidoses and Allied Disorders. Advances in Experimental Medicine and Biology, vol 19. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6570-0_43

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  • DOI: https://doi.org/10.1007/978-1-4757-6570-0_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-6572-4

  • Online ISBN: 978-1-4757-6570-0

  • eBook Packages: Springer Book Archive

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