Abstract
Micelles and microemulsions are elegant systems for drug delivery through solubilization of lipophilic drugs and transdermal or parenteral application of drugs. The disadvantage of such systems is mainly the lack of shelf stability and poor resistance to heat which is necessary for antimicrobial treatment. The main reason for this instability is the loose and mobile liquid nature of the micelle membrane and consequently the high degree of molecular motions, and the varying permeability for drug molecules with changing temperatures. One way to eliminate this instability could be to harden the micelle itself or its membrane, so as to get a vesicle with a solid amorphous wall.
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© 1984 Springer Science+Business Media New York
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Speiser, P. (1984). Hardened Reverse Micelles as Drug Delivery Systems. In: Luisi, P.L., Straub, B.E. (eds) Reverse Micelles. Forschung Soziologie. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6424-6_30
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DOI: https://doi.org/10.1007/978-1-4757-6424-6_30
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