The Advantages and Disadvantages of Randomised Controlled Trials

  • Christopher J. Bulpitt
Part of the Developments in Biostatistics and Epidemiology book series (DBEP, volume 1)


This chapter reviews the advantages and disadvantages of performing randomised controlled trials. Observational studies may fail to include controls or may use an inappropriate comparison group. The advantage of the randomised controlled trial lies in the greater confidence with which we can accept the results. Randomised controlled trials have prevented the introduction and continued use of useless and dangerous treatments.


Randomise Control Trial False Positive Result Small Trial Effective Randomisation Rare Adverse Effect 
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Copyright information

© Springer Science+Business Media Dordrecht 1983

Authors and Affiliations

  • Christopher J. Bulpitt
    • 1
    • 2
    • 3
  1. 1.Department of Medical Statistics and EpidemiologyLondon School of Hygiene and Tropical MedicineLondonUK
  2. 2.Royal Postgraduate Medical SchoolLondonUK
  3. 3.Hammersmith HospitalLondonUK

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