Abstract
Animal models have had a major role in shaping our current understanding of diabetes, and should become even more important in the future. Two major purposes of animal models are to improve understanding the physiology of diabetes and promote development of new therapeutic compounds. Important contributions have come from both classical laboratory animal models and new ones made using advanced methods of genetic manipulation. This chapter reviews the different types of animal models, with emphasis on the more commonly used and informative animals. Models of type 1 diabetes, type 2 diabetes, and obesity are considered. For further information, the reader is referred to the more detailed reviews listed at the end of this chapter.1,2
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Haluzik, M., Reitman, M.L. (2004). Animal Models of Diabetes. In: Poretsky, L. (eds) Principles of Diabetes Mellitus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6260-0_8
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DOI: https://doi.org/10.1007/978-1-4757-6260-0_8
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-6262-4
Online ISBN: 978-1-4757-6260-0
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