Exercise in the Therapy of Diabetes Mellitus

  • Stephen H. Schneider
  • Rajiv Bhambri


Exercise has been advocated for patients with diabetes for many years but it was only little over a decade ago that the American Diabetes Association felt there was enough evidence of benefit to recommend exercise as a routine part of the treatment of type 2 diabetes mellitus. Our understanding of the complex interactions of exercise with diabetes is still incomplete and the most effective ways to use exercise in the treatment of the disease are still under investigation. During exercise major cardiorespiratory and circulatory responses occur to efficiently supply the increased oxygen and energy needs of the working muscles. Whole body oxygen consumption and glucose turnover may increase more than ten fold and even greater increases may occur in the skeletal muscles.1 In healthy individuals, a complex hierarchy of hormonal responses regulates the needed alterations in fuel metabolism necessary to maintain normal plasma glucose levels during prolonged activity.2 This metabolic response to exercise may be severely disordered in patients with diabetes mellitus. In order to understand the effects of diabetes on fuel metabolism during exercise, it is important to first review the normal physiology.


Resistance Training Physical Training Prolonged Exercise Insulin Resistance Syndrome High Intensity Exercise 
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© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Stephen H. Schneider
  • Rajiv Bhambri

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