Abstract
During the past three decades, the incidence of esophageal adenocarcinoma (EAC) in the US increased by 5- to 6-fold, with a yearly increase of 4–10%.1 The prognosis for EAC is extremely poor, and the 5 year survival rate is ~10%.1−3 Despite significant improvements in early diagnosis and treatment, the majority of deaths in EAC patients are attributable to metastases that are resistant to therapy.2,3
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Ding, I., Okunieff, P., Liu, W., Fenton, B., Salnikow, K. (2003). A New Intrinsic Hypoxia Marker in Esophageal Cancer. In: Thorniley, M., Harrison, D.K., James, P.E. (eds) Oxygen Transport to Tissue XXV. Advances in Experimental Medicine and Biology, vol 540. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6125-2_32
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DOI: https://doi.org/10.1007/978-1-4757-6125-2_32
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