Sensing Improvement of Protein C Biosensor by Sample Circulation

  • Liang Tang
  • Kyung A. Kang
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 540)


Protein C (PC) is one of the most important proteins involved in the blood hemostasis. It is a potent anticoagulant, antithrombotic, and anti-inflammatory agent. Individuals with heterozygous PC deficiency have, by the age of 40, an 8–10 times higher risk of the thrombotic complications1. Accordingly, PC deficiency may lead to problems of oxygen and nutrient transport to tissue. Therefore, early diagnosis of PC deficiency is crucial to prevent thrombo-embolic episodes, such as, lung embolism, stroke, and/or heart attack.


Incubation Time Assay Time Circulation Velocity Human Serum Albumin Solution Lung Embolism 
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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Liang Tang
    • 1
  • Kyung A. Kang
    • 1
  1. 1.Department of Chemical EngineeringUniversity of LouisvilleLouisvilleUSA

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