Introduction to Medical Applications

  • A. J. Welch
  • Martin J. C. Van Gemert
Part of the Lasers, Photonics, and Electro-Optics book series (LPEO)


The first two parts of this book describe various theories associated with light propagation in tissue and the resulting thermal response. We assume that the transport equation governs the optical interaction of light with tissue and the heat conduction equation provides the basis for estimating the thermal response of tissue to laser radiation. In Part III of this book, the theory for optical and thermal interactions of laser light with tissue are used to analyze medical applications. In particular, the concepts of Parts I and II
  1. (a)

    can describe the optical and thermal interaction of therapeutic applications of lasers;

  2. (b)

    can estimate dosimetry requirements for photochemical and thermal clinical treatments;

  3. (c)

    can provide predictive information for design of medical systems; and

  4. (d)

    can provide a framework for interpreting optical and thermal measurements, especially for diagnostic applications.



Target Vessel Fluence Rate Thermal Interaction Port Wine Stain Selective Photothermolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Gemert MJC van, Cheong W-F, Welch AJ, Star WM. “Light delivery for whole-bladder photodynamic therapy,” Lasers Med. Sci. 2: 273–283 (1987).Google Scholar
  2. 2.
    Marijnissen JPA, Star WM, In’t Zandt HJA, D’Hallewin MA, Baert L. “In situ dosimetry during whole bladder wall photodynamic therapy: clinical results and experimental verification,” Phys. Med. Biol. 37: 1–16 (1993).Google Scholar
  3. 3.
    Jerath MR, Kaisig D, Rylander III HG, Welch AJ. “Calibrated real time control of lesion size based on reflectance images,” Appl. Opt. 32(7): 1200–1209 (1993).Google Scholar
  4. 4.
    Essenpries M. “Thermally induced changes in optical properties of biological tissues,” PhD Thesis, University of London, December 1992.Google Scholar
  5. 5.
    Costello AJ, Douglas DE, Bolton DM. “Nd:YAG laser ablation of the prostate as a treatment for benign prostatic hypertrophy,” Lasers Surg. Med. 12: 121–124 (1992).Google Scholar
  6. 6.
    Anderson RR, Parrish JA. “Microvasculature can be selectively damaged using dye lasers: A basic theory and experimental evidence in human skin,” Lasers Surg. Med. 1: 263–270 (1981).Google Scholar
  7. 7.
    Gemert MJC van, Hulsbergen Henning JP. “A model approach to laser coagulation of dermal vascular lesions,” Arch. Dermatol. Res. 270: 429–439 (1981).Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • A. J. Welch
    • 1
  • Martin J. C. Van Gemert
    • 2
  1. 1.Department of Electrical and Computer EngineeringThe University of Texas at AustinAustinUSA
  2. 2.Laser CenterAcademic Medical CenterAmsterdamThe Netherlands

Personalised recommendations