Structure and Reaction Mechanism of the β-Glycosidase from the Archaeon Sulfolobus Solfataricus
Hyperthermophilic Bacteria and Archaea represent the organisms at the upper-temperature border of life. They have been almost exclusively isolated from environments with temperatures between 80 and 115°C, such as hot springs, solfatara fields, submarine hydrothermal areas or abyssal hot-vent systems (Brock, 1986). In particular, hyperthermophilic microorganisms living in marine abyssal biotopes grow optimally in presence of combined stress factors, for istance high pressure and temperatures above 100°C. Most of the microorganisms growing around 100°C belong to Archaea (formerly the archaebacteria) one of the three domains of the living world. On the basis of the recent hypothesis that life appeared at high temperatures, it has been proposed that archaeal hyperthermophiles could be the most ‘primitive’ living organisms and the closest to the universal ancestor.
KeywordsGlycosyl Hydrolase Glu206 Residue Transglycosylating Activity SULFOLOBUS SOLFATARICUS Hyperthermophilic Bacterium
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