Expression of Thyroid Hormone Receptor-α in the Growth and Development of the Sea Bream (Sparus Aurata)
Thyroid hormones (THs) play a number of roles in vertebrate organisms. In mammals, in addition to influencing basic metabolic rate, THs affect prenatal and post-natal development, with transgenic mice lacking the thyroid hormone receptor (TR)-α dying within a few weeks of birth, apparently due to an inability to complete some of the maturation processes required for survival in the post-weaning period (Fraichard et al., 1997). Additionally, TH deficiency during differentiation causes a number of abnormalities including neurological and skeletal defects.
KeywordsBasic Metabolic Rate Thyroid Hormone Receptor Skeletal Defect Salmon Smoltification High Amino Acid Identity
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