Agonist Bindings and their Relationship to Receptor Responses in Heart Muscarinic Receptors

  • Shuji Uchida
  • Atsushi Mizushima
  • Xiao-Ming Zhou
  • Hiroshi Yoshida
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 236)


The presence of two subtypes in muscarinic acetylcholine receptors (m-AChR) was well established. One is the M1 subtype, neuronal m-AChR, and the other is M2 subtype, peripheral m-AChR. Now, the presence of many more subtypes is suggested by the evidences from pharmacology and gene technology.


Adenylate Cyclase Guanine Nucleotide Muscarinic Acetylcholine Receptor Muscarinic Agonist Agonist Binding 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Shuji Uchida
    • 1
  • Atsushi Mizushima
    • 1
  • Xiao-Ming Zhou
    • 1
  • Hiroshi Yoshida
    • 1
  1. 1.Department of Pharmacology IOsaka University School of MedicineKitaku, Osaka 530Japan

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