Receptor-Stimulated System Mediated Interactions of Neuropeptides in GH3 Cells

  • N. Ogawa
  • K. Haba
  • S. Hirakawa
  • K. Mizukawa
  • T. Tsushima
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 236)


After the discovery of the coexistence of neuropeptides and classical neurotransmitters or neuropeptides, many reports have appeared about the coexistence of neurotransmitters in various central and peripheral neuronal systems (1,2). However, evidence has only been presented indicating the coexistence of these substances, and it is not known whether or not this coexistence has important physiological function. Such coexistence motivated us to examine the interactions of not only cotransmitters but also neuropeptides in different families.


Adenylate Cyclase Membrane Fraction Vasoactive Intestinal Peptide Phorbol Ester Pituitary Cell 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • N. Ogawa
    • 1
  • K. Haba
    • 1
  • S. Hirakawa
    • 2
  • K. Mizukawa
    • 3
  • T. Tsushima
    • 4
  1. 1.Institute for NeurobiologyOkayama University Medical SchoolShikatacho, Okayama 700Japan
  2. 2.Dept. of Medicine 3Okayama University Medical SchoolShikatacho, Okayama 700Japan
  3. 3.Dept. of AnatonyOkayama University Medical SchoolShikatacho, Okayama 700Japan
  4. 4.Dept. of Medicine 2Tokyo Women’s Medical CollegeShinjukuku, Tokyo 162Japan

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