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Apoptosis, Cancer, and Cancer Therapy

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Book cover Molecular Mechanisms of Programmed Cell Death

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Abstract

Apoptosis is a complex process involving a large array of genes and mutation of any of these genes may lead to malignancy formation. Tumor cells may actively evade the immune surveillance by actively inducing the apoptosis of effector lymphocytes, facilitating mass formation and metastasis. Apart from traditional therapies inducing tumor cell apoptosis, new strategies employing death receptor ligands and making use of tumor counterattack are also being developed.

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Authors and Affiliations

  1. International Joint Cancer Institute, The Second Military Medical University, Shanghai, 200433, People’s Republic of China

    Dr. Yajun Guo

  2. Epply Cancer Institute, University of Nebraska Medical Center, Omaha, NE, 68198-6805., USA

    Dr. Yajun Guo

Authors
  1. Xiao Qiang Fan
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  2. Hao Wang
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  3. Weizhu Qian
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  4. Dr. Yajun Guo
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Corresponding author

Correspondence to Yajun Guo .

Editor information

Editors and Affiliations

  1. Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey, USA

    Yufang Shi

  2. National Institutes of Health, Research Triangle Park, North Carolina, USA

    John A. Cidlowski

  3. American Red Cross, Rockville, Maryland, USA

    David Scott

  4. Chinese Academy of Sciences, Shanghai, China

    Jia-Rui Wu

  5. National Institutes of Health, Bethesda, Maryland, USA

    Yun-Bo Shi

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Fan, X.Q., Wang, H., Qian, W., Guo, Y. (2003). Apoptosis, Cancer, and Cancer Therapy. In: Shi, Y., Cidlowski, J.A., Scott, D., Wu, JR., Shi, YB. (eds) Molecular Mechanisms of Programmed Cell Death. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5890-0_14

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  • DOI: https://doi.org/10.1007/978-1-4757-5890-0_14

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