Apoptosis, Cancer, and Cancer Therapy

  • Xiao Qiang Fan
  • Hao Wang
  • Weizhu Qian
  • Yajun Guo


Apoptosis is a complex process involving a large array of genes and mutation of any of these genes may lead to malignancy formation. Tumor cells may actively evade the immune surveillance by actively inducing the apoptosis of effector lymphocytes, facilitating mass formation and metastasis. Apart from traditional therapies inducing tumor cell apoptosis, new strategies employing death receptor ligands and making use of tumor counterattack are also being developed.


Death Receptor Death Domain Isolate Limb Perfusion FasL Expression Death Receptor Pathway 
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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Xiao Qiang Fan
  • Hao Wang
  • Weizhu Qian
  • Yajun Guo
    • 1
    • 2
  1. 1.International Joint Cancer InstituteThe Second Military Medical UniversityShanghaiPeople’s Republic of China
  2. 2.Epply Cancer InstituteUniversity of Nebraska Medical CenterOmahaUSA

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