Abstract
During development of the nervous system, several morphogenetic processes act together to establish its orderly structure by generating specific nerve connections. The steps involved in neural pattern formation include cell differentiation, cell migration, axonal outgrowth, target recognition and synapse formation. Earlier, these processes were only characterized at the morphological level although it was obvious that adhesive interactions between cell surfaces and the extracellular milieu were of central importance. Several systems mediating cell-cell or cell-substratum adhesion have now been identified on the surface of neural cells and described at the molecular level (Jessell, 1988; Rutishȧuser and Jessell, 1988).
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Nybroe, O., Bock, E. (1990). Structure and Function of the Neural Cell Adhesion Molecules NCAM and L1. In: Lauder, J.M., Privat, A., Giacobini, E., Timiras, P.S., Vernadakis, A. (eds) Molecular Aspects of Development and Aging of the Nervous System. Advances in Experimental Medicine and Biology, vol 265. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5876-4_18
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DOI: https://doi.org/10.1007/978-1-4757-5876-4_18
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