Abstract
As we learn more about the process of carcinogenesis it is becoming clear that several oncogenes are involved in growth and differentiation of cells. There is also growing evidence for a role of proto-oncogene products in differentiation for example in the neuronal and hemopoietic lineages (for a review see ref.l). Proliferation and differentiation appear to be interdependent processes, in that a cycle of cell division often seems to be a prerequisite for differentiation. Further growth factors are frequently also differentiation factors.
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Spandidos, D.A., Anderson, M.L.M. (1990). A Role of Ras Oncogenes in Carcinogenesis and Differentiation. In: Lauder, J.M., Privat, A., Giacobini, E., Timiras, P.S., Vernadakis, A. (eds) Molecular Aspects of Development and Aging of the Nervous System. Advances in Experimental Medicine and Biology, vol 265. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5876-4_11
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