Abstract
In recent years, our understanding of motor behavior in terms of single-cell activity has been primarily concerned with determining the functional structure of central pattern generators (CPGs) (Selverston, 1980). To analyze such a structure, i.e., to identify the neuronal components and determine the mutual interactions between these components, “naked” CPGs (i.e., completely deafferented CPGs) must be used. Nevertheless, the patterned activity that can be recorded from such an isolated CPG is relatively stereotyped, and until now, little was known about the mechanisms by which such a network could exhibit flexibility in its output in the intact animal. The goal of this chapter is to show how extrinsic inputs to a well-known CPG (the pyloric network of Crustacea, see Chapter 3, this volume) can continuously control the expression of the intrinsic properties of the neurons and thereby continuously “rewire” the network.
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References
Anderson, W. W., and Barker, D. L., 1981, Synaptic mechanisms that generate network oscillations in the absence of discrete postsynaptic potentials, J. Exp. Zool. 216:187–191.
Barker, J. L., and Gainer, H., 1974, Peptide regulation of bursting pacemaker activity in a molluscan neurosecretory cell, Science 184:1371–1373.
Barker, J. L., Ifshin, M., and Gainer, H., 1975, Studies on bursting pacemaker potential activity in molluscan neurons. III. Effects of hormones, Brain Res. 84:501–513.
Cooke, I. M., and Hartline, D. K., 1975, Neurohormonal alterations of integrative properties of the cardiac ganglion of the lobster Homaros americanus, J. Exp. Biol. 63:33–52.
Delcomyn, F., 1980, Neural basis of rhythmic behavior in animals, Science 210:492–498.
Dickinson, P. S., and Nagy F., 1983, Control of a central pattern generator by an identified modulatory interneurone in Crustacea. II. Induction and modification of plateau properties in pyloric neurones, J. Exp. Biol. 105:59–82.
Eisen, J. S., and Marder, E., 1984, A mechanism for the production of phase shifts in a pattern generator, J. Neurophysiol. 51:1375–1393.
Gagerman, E., Idahl, L. A., Meissner, H. P., and Taljedal, I. B., 1978, Insulin release, cGmP, cAMP and membrane potential in acetylcholine stimulated islets, Am. J. Physiol. 235:493–500.
Giles, W., and Noble, S. J., 1976, Changes in membrane currents in bullfrog atrium produced by acetylcholine, J. Physiol. (London) 276:103–123.
Gola, M., and Selverston, A. I., 1981, Ionic requirements for bursting activity in lobster stomatogastric neurones, J. Comp. Physiol. 145:191–207.
Grillner, S., 1975, Locomotion in vertebrates, central mechanisms and reflex interaction, Physiol. Rev. 55:247–304.
Grillner, S., 1977, On the neural control of movement. A comparison of different basic rhythmic behaviors, in: Function and Formation of Neural Systems (G. S. Stent, ed.), Dahlem Konferenzen, Berlin, pp. 197–224.
Ifshin, M., Gainer, H., and Barker, J. L., 1975, Peptide factor extracted from molluscan ganglia that modulates bursting pacemaker activity, Nature (London) 254:72–73.
Ikeda, K., and Wiersma, C. A. G., 1964, Autogenic rhythmicity in the abdominal ganglia of the crayfish: The control of swimmeret movements, Comp. Biochem. Physiol. 12:107–115.
Kits, K. S., and Bos, N. P. A., 1981, Pacemaking mechanisms of the after discharge of the ovulation hormone-producing caudo-dorsal cells in the gastropod mollusc, Lymnaea stagnalis, J. Neurobiol. 12:425–439.
Kristan, W. B., and Guthrie, P. B., 1977, Acquisition of swimming behavior in chronically isolated single segment of the leech, Brain Res. 131:191–195.
Lemos, J. R., and Berlind, A., 1981, Cyclic adenosine monophosphate mediation of peptide neurohormone effects on the lobster cardiac ganglion, J. Exp. Biol. 90:307–326.
Marder, E., 1984, Mechanisms underlying neurotransmitter modulation of a neuronal circuit, Trends Neurosci. 7:48–53.
Marder, E., and Eisen, J. S., 1984, Electrically coupled pacemaker neurons respond differently to the same physiological inputs and neurotransmitters, J. Neurophysiol. 51:1362–1374.
Mayeri, E., Brownel, P., Branton, W. D., and Simon, S. B., 1979, Multiple, prolonged actions of neuroendocrine bag cells on neurons in Aplysia, I. Effects on bursting pacemaker neurons, J. Neurophysiol. 42:1165–1184.
Maynard, D. M., 1972, Simpler networks, Ann. NY. Acad. Sci. 193:59–72.
Miller, J. P., and Selverston, A. I., 1982, Mechanisms underlying pattern generation in lobster stomatogastric ganglion as determined by selective inactivation of identified neurons, II. Oscillatory properties of pyloric neurons, J. Neurophysiol. 48:1378–1391.
Moulins, M., and Cournil, I., 1982, All-or-none control of the bursting properties of the pacemaker neurons of the lobster pyloric pattern generator, J. Neurobiol. 13:447–458.
Moulins, M., and Nagy, F., 1983, Control of integration by exogenous inputs in crustacean neuronal circuits, J. Physiol (Paris) 78:755–764.
Nagy, F., 1981, Etude de l’expression d’activités motrices rythmiques organisées par des générateurs paucineuroniques du système nerveux stomatogastrique des Crustacés décapodes. Flexibilité intrinsèque aux réseaux moteurs; contrôle par les centres supérieurs; contrôle proprioceptif, Thèse d’Etat Université de Bordeaux I.
Nagy, F., and Dickinson, P. S., 1983, Control of a central pattern generator by an identified modulatory interneurone in Crustacea, I. Modulation of the pyloric motor output, J. Exp. Biol. 105:33–58.
Nagy, F., Dickinson, P. S., and Moulins, M., 1981, Modulatory effects of a single neuron on the activity of the pyloric pattern generator in Crustacea, Neurosci. Lett. 23:167–173.
Nagy, F., Benson, J. A., and Moulins, M., 1984, Cholinergic activation of burst generating oscillations mediated by opening of Ca++ channels in lobster pyloric neurons, Soc. Neurosa. Abstr. 10:148.
Parnas, I., Armstrong, D., and Strumwasser, F., 1974, Prolonged excitatory and inhibitory synaptic modulation of a bursting pacemaker neuron, J. Neurophysiol. 37:594–608.
Raper, J. A., 1979, Nonimpulse mediated synaptic transmission during the generation of a cyclic motor program, Science 205:304–306.
Reuter, H., 1974, Localization of beta-adrenergie receptors and effects of noradrenaline and cyclic nucleotides on action potentials, ionic currents and tension in mammalian cardiac muscle, J. Physiol. (London) 242:429–451.
Rezer, E., and Moulins, M., 1983, Expression of the crustacean pyloric pattern generator in the intact animal, J. Comp. Physiol. 153:17–28.
Robertson, R. M., and Moulins, M., 1981, Oscillatory command input to the motor pattern generators of the crustacean stomatogastric ganglion, I. The pyloric rhythm, J. Comp. Physiol. 143:453–463.
Russell, D. F., and Hartline, D. K., 1978, Bursting neural networks: A reexamination, Science 200:453–456.
Selverston, A. I., 1980, Are central pattern generators understandable, Behav. Brain Sci. 3:535–571.
Selverston, A. I., and Miller, J. P., 1980, Mechanisms underlying pattern generation in lobster stomatogastric ganglion as determined by selective inactivation of identified neurons, I. Pyloric system, J. Neurophysiol. 44:1102–1121.
Selverston, A. I., Russell, D. F., Miller, J. P., and King, D. G., 1976, The stomatogastric nervous system: Structure and function of a small neural network, Prog. Neurobiol. 7:215–290.
Stein, P. S. G., 1977, Application of the mathematics of coupled oscillator systems to the analysis of the neural control of locomotion, Fed. Proc. 36:2056–2059.
Stein, P. S. G., 1978, Motor systems with specific reference to the control of locomotion, Annu. Rev. Neurosci. 1:61–81.
Ten Eick, R., Nawrath, H., McDonald, T. F., and Trautwein, W., 1976, On the mechanism of the negative inotropic effect of acetylcholine, Pflug. Arch. Eur. J. Physiol. 361:207–213.
Watanabe, A., Obara, S., and Akiyama, T., 1969, Acceleratory synapses on pacemaker neurons in the heart ganglion of a stomatopod, Squilla oratoria, J. Gen. Physiol. 54:212–231.
Wilson, D. M., and Wyman, R. J., 1965, Motor output patterns during random and rhythmic stimulations of locust thoracic ganglia, Biophysiol. J. 5:121–143.
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Moulins, M., Nagy, F. (1985). Extrinsic Inputs and Flexibility in the Motor Output of the Lobster Pyloric Neural Network. In: Selverston, A.I. (eds) Model Neural Networks and Behavior. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5858-0_4
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DOI: https://doi.org/10.1007/978-1-4757-5858-0_4
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