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The Development of Serotonin-containing Neurons in the Leech

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Abstract

Given the rapid deployment of new experimental techniques in the last decade, many of the important questions in developmental neurobiology appear to be nearing their resolution. One of these questions is that of how each nerve cell acquires its differentiated characteristics: the appropriate membrane channels and receptors, the capacity to produce and store the appropriate transmitter(s), the correct pattern of process outgrowth, and, finally, the establishment of connections of just the right type and strength with just the right constellation of neurons to produce proper behaviors.

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References

  • Bate, C. M., 1976, Embryogenesis of an insect nervous system. I. A map of the thoracic and abdominal neuroblasts in Locusta migratoria, J. Embryol. Exp. Morphol. 35:107–123.

    PubMed  CAS  Google Scholar 

  • Blair, S. S., 1982, Blastomere ablation and the developmental origins of identified monoamine-contain-ing neurons in the leech, Dev. Biol. 95:65–72.

    Article  Google Scholar 

  • Blair, S. S., and Weisblat, D. A., 1982, Ectodermal interactions during neurogenesis in the glossiphoniid leech Helobdella triserialis, Dev. Biol. 76:245–262.

    Google Scholar 

  • Fernandez, J. H., 1980, Embryonic development of the glossiphoniid leech Theromyzon rude: Characterization of developmental stages, Dev. Biol. 76:245–262.

    Article  PubMed  CAS  Google Scholar 

  • Fernandez, J. H., and Olea, N., 1982, Embryonic development of glossiphoniid leeches, in: Developmental Biology of Freshwater Invertebrates, Alan R. Liss, New York, pp. 317–361.

    Google Scholar 

  • Fuchs, P. A., Henderson, L. P., and Nicholls, J. G., 1982, Chemical transmission between individual Retzius and sensory neurones of the leech in culture, J. Physiol. (London) 323:195–210.

    CAS  Google Scholar 

  • Glover, J. C, and Kramer, A. P., 1982, Serotonin analog selectively ablates identified neurons in the leech embryo, Science 216:317–319.

    Article  PubMed  CAS  Google Scholar 

  • Glover, J. C, and Stuart, D. K., 1983, Differentiation of serotonin-containing neurons in the leech, Soc. Neurosci. Abstr. 9:606.

    Google Scholar 

  • Goodman, C. S., and Pearson, K. G. (eds.), 1982, Neuronal development: Cellular approaches in invertebrates, NRP Bull. 20:777–942.

    Google Scholar 

  • Goodman, C. S., O’Shea, M., McCaman, R. E., and Spitzer, N. C., 1979, Embryonic development of identified neurons: Temporal pattern of morphological and biochemical differentiation, Science 204:1219–1222.

    Article  PubMed  CAS  Google Scholar 

  • Henderson, L. P., 1983, The role of 5-hydroxytryptamine as a transmitter between identified leech neurones in culture, J. Physiol. (London) 339:309–324.

    CAS  Google Scholar 

  • Hockfield, S., and McKay, R., 1983, Monoclonal antibodies demonstrate the organization of axons in the leech, J. Neurosci. 3:369–375.

    PubMed  CAS  Google Scholar 

  • Jeffery, W. R., Tomlinson, C. R., and Brodeur, R. D., 1983, Localization of actin messenger RNA during early ascidian development, Dev. Biol. 99:408–417.

    Article  PubMed  CAS  Google Scholar 

  • Kramer, A. P., and Kuwada, J. Y., 1983, Formation of the receptive fields of leech sensory neurons during embryonic development, J. Neurosci. 3:2474–2486.

    PubMed  CAS  Google Scholar 

  • Kramer, A. P., and Weisblat, D. A., 1985, Developmental neural kinship groups in the leech, J. Neurosci. 5:(in press).

    Google Scholar 

  • Kristan, W. B., Jr., and Nusbaum, M. P., 1983, The dual role of serotonin in leech swimming, J. Physiol. (Paris) 78:743–747.

    CAS  Google Scholar 

  • Kuwada, J. Y., 1984, Normal and abnormal development of an identified leech motor neuron, J. Embryol. Exp. Morphol. 79:125–137.

    PubMed  CAS  Google Scholar 

  • Kuwada, J. Y., and Kramer, A. P., 1983, Early embryonic development of identified sensory neurons in the leech CNS, J. Neurosci. 3:2098–3111.

    PubMed  CAS  Google Scholar 

  • Lent, C. M., 1973, Retzius cells: NeuroefFectors controlling mucus release by the leech, Science 179:693–696.

    Article  PubMed  CAS  Google Scholar 

  • Lent, C. M., 1982, Fluorescent properties of monoamine neurons following glyoxylic acid treatment of intact leech ganglia, Histochemistry 75:77–89.

    Article  PubMed  CAS  Google Scholar 

  • Lent, C. M., Dickinson, M. H., and Marshall, C. G., 1983, Serotonin controls feeding behavior in the medicinal leech, Soc. Neurosci. Abstr. 9:913.

    Google Scholar 

  • Li, C., and Calabrese, R. L., 1983, Evidence for proctolin-like substances in the central nervous system of the leech, Soc. Neurosci. Abstr. 9:76.

    Google Scholar 

  • Mason, A., and Kristan, W. B., Jr., 1982, Neuronal excitation, inhibition and modulation of leech longitudinal muscle, J. Comp. Physiol. 146:527–536.

    Article  Google Scholar 

  • Mason, A., Sunderland, A. J., and Leake, L. D., 1979, Effects of leech Retzius cells on body wall muscles, Comp. Biochem. Physiol Comp. Pharmacol. 63:359–361.

    Article  Google Scholar 

  • Muller, K. J., Nicholls, J. G., and Stent, G. S. (eds.), 1981, The Neurobiology of the Leech, Cold Spring Harbor Press, New York.

    Google Scholar 

  • Ready, D., and Nicholls, J. G., 1979, Identified neurones from leech CNS make selective connections in culture, Nature (London) 281:67–69.

    Article  CAS  Google Scholar 

  • Shankland, M., 1984, Positional determination of supernumerary blast cell death in the leech embryo, Nature (London) 307:9–15.

    Article  Google Scholar 

  • Shankland, M., and Weisblat, D. A., 1984, Stepwise commitment of blast cell fates during the positional specification of the O and P cell lines in the leech embroy, Dev. Biol. 106:326–342.

    Article  PubMed  CAS  Google Scholar 

  • Stewart, R. R., and Macagno, E. R., 1984, The development of segmental differences in cell number in the CNS of the leech, Soc. Neurosci. Abstr. 10:512.

    Google Scholar 

  • Stuart, A. E., Hudspeth, A. J., and Hall, Z. W., 1974, Vital staining of specific monoamine-containing cells in the leech nervous system, Cell Tissue Res. 153:55–61.

    Article  PubMed  CAS  Google Scholar 

  • Stuart, D. K., Glover, J. C, Blair, S. S., and Weisblat, D. A., 1983, Development of leech serotonin neurons examined with serotonin antibody, cell lineage tracer and cell killing, Soc. Neurosci. Abstr. 9:604.

    Google Scholar 

  • Sulston, J. E., Schierenberg, E., White, J. G., and Thomson, J. N., 1983, The embryonic development of the nematode Caenorhabditis elegans, Dev. Biol. 100:64–119.

    Article  CAS  Google Scholar 

  • Weisblat, D. A., and Blair, S. S., 1984, Developmental indeterminacy in embryos of the leech Helobdella triserialis, Dev. Biol. 101:326–335.

    Article  CAS  Google Scholar 

  • Weisblat, D. A., Sawyer, R. T., and Stent, G. S., 1978, Cell lineage analysis by intracellular injection of a tracer enzyme, Science 202:1295–1298.

    Article  PubMed  CAS  Google Scholar 

  • Weisblat, D. A., Harper, G., Stent, G. S., and Sawyer, R. T., 1980a, Embryonic cell lineages in the nervous system of the glossiphoniid leech Helobdella triserialis, Dev. Biol. 76:58–78.

    Article  CAS  Google Scholar 

  • Weisblat, D. A., Zackson, S. L., Blair, S. S., and Young, J. D., 1980b, Cell lineage analysis by intracellular injection of fluorescent tracers, Science 209:1538–1541.

    Article  PubMed  CAS  Google Scholar 

  • Weisblat, D. A., Kim, S. Y., and Stent, G. S., 1984, Cell lineage in the development of the leech Helobdella triserialis, Dev. Biol. 104:65–85.

    Article  CAS  Google Scholar 

  • Whitman, C. O., 1878, The embryology of Clepsine, Q.J. Microsc. Sci. (N.S.) 18:215–315.

    Google Scholar 

  • Whitman, C. O., 1892, The metamerism of Clepsine, in: Festschrift zum 70. Geburtstage R. Leuckarts, Engelman, Leipzig, pp. 385–395.

    Google Scholar 

  • Whittaker, J. R., 1982, Muscle lineage cytoplasm can change the developmental expression in epidermal lineage cells of ascidian embryos, Dev. Biol. 93:463–470.

    Article  PubMed  CAS  Google Scholar 

  • Willard, A. L., 1981, Effects of serotonin on the generation of the motor program for swimming by the medicinal leech, J. Neurosci. 1:936–944.

    PubMed  CAS  Google Scholar 

  • Zackson, S. L., 1982, Cell clones and segmentation in leech development, Cell 31:761–770.

    Article  PubMed  CAS  Google Scholar 

  • Zackson, S. L., 1984, Cell lineage, cell interactions and segment formation in the embryo of a glossiphoniid leech, Dev. Biol. 104:143–160.

    Article  PubMed  CAS  Google Scholar 

  • Zipser, B., Stewart, R., Flanagan, T., Flaster, M., and Macagno, E., 1984, Do monoclonal antibodies stain sets of functionally related leech neurons? Cold Spring Harbor Symp. Quant. Biol. 48:551–556.

    Article  Google Scholar 

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Weisblat, D.A., Kristan, W.B. (1985). The Development of Serotonin-containing Neurons in the Leech. In: Selverston, A.I. (eds) Model Neural Networks and Behavior. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5858-0_10

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  • DOI: https://doi.org/10.1007/978-1-4757-5858-0_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-5860-3

  • Online ISBN: 978-1-4757-5858-0

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