Electron Microscopic Methods in Membrane Biology

  • H. P. Zingsheim
  • H. Plattner


Modern membranology started exactly half a century ago: In 1925 Fricke published his capacity measurements on erythrocyte suspensions. This led to the conclusion that the cells are bounded by a thin hydrocarbon sheet approximately 50 Å thick. In the same year, applying Langmuir’s (1917) monolayer method, Gorter and Grendel (1925) inferred the arrangement of the lipids in the form of a bilayer within the erythrocyte membrane.


Erythrocyte Membrane Osmium Tetroxide Negative Staining Membrane Biology Hydroxypropyl Methacrylate 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • H. P. Zingsheim
    • 1
    • 2
    • 3
  • H. Plattner
    • 1
    • 2
    • 3
  1. 1.Max-Planck Institut für Biophysikalische Chemie, (Karl-Friedrich-Bonhoeffer Institut)GöttingenGermany
  2. 2.Institut für Zellbiologie der UniversitätMünchenGermany
  3. 3.Institut für Biochemie und Experimentelle Krebsforschung der UniversitätInnsbruckAustria

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