Acute Right Ventricular Failure: Physiology and Therapy

  • E. Renaud
  • P. Karpati
  • A. Mebazaa


The right ventricle (RV) has long been considered as a negligible entity, a simple passive passageway between the systemic venous and pulmonary circulations. As far back as 1943, physiologists were studying the hemodynamic effects following destruction of the RV free wall. As long as the conditions of ventricular filling were physiologic, there was no observed change in cardiac output. Subsequently, for the ensuing decades, little research into the RV and its physiologic role was conducted [1]. Progress in the comprehension of cardiovascular physiologic mechanisms paved the way for the discovery of the RV’s fundamental role in maintaining right atrial pressure (RAP) as low as possible, with the aim of assuring an optimal venous return.


Right Ventricle Pulmonary Capillary Wedge Pressure Right Atrial Pressure Mixed Venous Oxygen Saturation Right Ventricle Function 
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© Springer Science+Business Media New York 2002

Authors and Affiliations

  • E. Renaud
  • P. Karpati
  • A. Mebazaa

There are no affiliations available

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