Abstract
Sepsis is a result of highly heterogeneous processes characterized by an involvement of multiple components and their interactions at each organizational level of the human body: genes, cells, tissues, organs. The complexity of the underlying biological and immunological processes has encouraged multiple types of research studies comprising a broad panel of clinical aspects. One of the lessons learned to date is that evaluation of new sepsis therapies has been hampered by fairly unspecific, clinically-based inclusion criteria which insufficiently reflect the molecular mechanisms [1].
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Russwurm, S., Deigner, H.P., Reinhart, K. (2003). Microarray Technology in Sepsis: Tool or Toy?. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-5548-0_6
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DOI: https://doi.org/10.1007/978-1-4757-5548-0_6
Publisher Name: Springer, New York, NY
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