Inhalation Therapy during Mechanical Ventilation

  • E. Kondili
  • C. Alexopoulou
  • D. Georgopoulos
Conference paper


Aerosol medications are commonly used in mechanically ventilated patients. Several classes of drugs with different properties and indications may be given by inhalation. In all cases, compared to the systemic route, inhaled therapy has the advantage that for a given therapeutic response, the drug dose is several-fold lower, while systemic absorption is negligible, thus, greatly minimizing the side effects. In addition, for some medications the systemic route either causes non-acceptable side effects or results in considerably inferior therapeutic response, rendering the inhaled route the method of choice of drug administration. Bronchodilators, corticosteroids, vasoactive drugs, surfactant, antibiotics, helium, and perfluorocarbons are the medications that can be given by inhalation during mechanical ventilation.


Acute Respiratory Distress Syndrome Fluticasone Propionate Respir Crit Meter Dose Inhaler Inhalation Therapy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • E. Kondili
  • C. Alexopoulou
  • D. Georgopoulos

There are no affiliations available

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