Decreased Mitogenic Response of Murine Spleen Cells Following Intraperitoneal Injection of Serovar-Specific Glycopeptidolipid Antigens from the Mycobacterium Avium Complex

  • Lucilla C. Hooper
  • William W. Barrow
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 239)


Mycobacteria in the Mycobacterium avium complex have recently become clinically important opportunistic pathogens with a demonstrated ability to cause severe disseminated infections in patients suffering from AIDS (6,7,9,13). Although there are a variety of other nontuberculous mycobacteria that can infect humans, it appears that only certain serovars of the MAC are the most common to be associated with individuals who have AIDS (14). It has been suggested that the increased number of MAC infections in AIDS patients may be due to an immunologic defect which selectively favors these mycobacteria over other nontuberculous mycobacteria (14).


Spleen Cell Peritoneal Macrophage Mycobacterium Avium Complex Nonadherent Cell Splenic Lymphocyte 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Lucilla C. Hooper
    • 1
  • William W. Barrow
    • 1
  1. 1.Department of Microbiology and ImmunologyTexas College of Osteopathic MedicineFort WorthUSA

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