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The Use of Antibodies to Identify Glycosphingolipids and to Localize Them in Tissues

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Gangliosides and Neuronal Plasticity

Part of the book series: FIDIA Research Series ((FIDIA,volume 6))

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Abstract

Antibodies to glycosphingolipids (GSLs) are used by many investigators to identify carbohydrate structures of GSLs and for localization of these compounds in tissue sections. Proper interpretation of these immunological data requires knowledge of certain principles of carbohydrate immunochemistry and these will be reviewed in the next section. Some recent immunocytochemical studies will be presented in the final section.

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Abbreviations

GSL:

glycosphingolipid

gal:

D-galactose

GlcNAc:

N-acetyl-D-glucosamine

GalNAc:

N-acetyl-D-galactosamine, Man, D-mannose

Rha:

L-rhammose

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© 1986 Springer-Verlag Berlin Heidelberg

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Marcus, D.M. (1986). The Use of Antibodies to Identify Glycosphingolipids and to Localize Them in Tissues. In: Tettamanti, G., Ledeen, R.W., Sandhoff, K., Nagai, Y., Toffano, G. (eds) Gangliosides and Neuronal Plasticity. FIDIA Research Series, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-5309-7_6

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  • DOI: https://doi.org/10.1007/978-1-4757-5309-7_6

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-5311-0

  • Online ISBN: 978-1-4757-5309-7

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