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Gangliosides and Neuronal Plasticity pp 309–325Cite as

Facilitated-Establishment of Contacts and Synapses in Neuronal Cultures: Ganglioside-Mediated Neurite Sprouting and Outgrowth

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Part of the book series: FIDIA Research Series ((FIDIA,volume 6))

Abstract

Gangliosides are natural components of the neuronal membranes, and their addition to cultures of cells of neural origin, or administration to animal with neurolesions was shown to modulate cell growth and differentiation, nerve regeneration and reinnervation (see the review by Ledeen, 1984).

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Abbreviations

CNS:

central nervous system

NGF:

nerve grouth factor

FCS:

fetal calf serum

GABA:

γ-aminobutyric acid

BME:

eagle’s basal medium

SCG:

superior cervical ganglion

cAMP:

adenosine 3’, 5’-cyclic monophosphate.

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, University of Göttingen, Robert-Koch-Str.40, D-3400, Göttingen, Federal Republic of Germany

    P. E. Spoerri

Authors
  1. P. E. Spoerri
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Editor information

Editors and Affiliations

  1. Dipartimento di Chimica e Biochimica Medica, Facoltà di Medicina e Chirurgia, Università di Milano, Milano, Italy

    Guido Tettamanti

  2. Dept of Neurology and Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA

    Robert W. Ledeen

  3. Institut für Organische, Chemie und Biochemie, Universität Bonn, Bonn, Germany

    Konrad Sandhoff

  4. Dept of Biochemistry, University of Tokyo, Tokyo, Japan

    Yoshitaka Nagai

  5. Dept of Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan

    Yoshitaka Nagai

  6. Research Laboratories, Fidia Neurobiological, Abano Terme, Italy

    Gino Toffano

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© 1986 Springer-Verlag Berlin Heidelberg

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Spoerri, P.E. (1986). Facilitated-Establishment of Contacts and Synapses in Neuronal Cultures: Ganglioside-Mediated Neurite Sprouting and Outgrowth. In: Tettamanti, G., Ledeen, R.W., Sandhoff, K., Nagai, Y., Toffano, G. (eds) Gangliosides and Neuronal Plasticity. FIDIA Research Series, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-5309-7_25

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  • DOI: https://doi.org/10.1007/978-1-4757-5309-7_25

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-5311-0

  • Online ISBN: 978-1-4757-5309-7

  • eBook Packages: Springer Book Archive

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