Abstract
Gangliosides (Fig. 1),although characteristic components of all mammalian plasma membranes, are highly abundant in nervous tissues only. They are arranged asymmetrically in the outer leaflet of cellular membranes, their carbohydrate chains facing the extracellular space. Little is known about their function and about the regulation of their metabolism, the elucidation of which might be helpful in understanding the pathogenetic mechanisms underlying the clinical symptoms of ganglioside storage diseases.
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© 1986 Springer-Verlag Berlin Heidelberg
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Hinrichs, U., Sonderfeld, S., Schwarzmann, G., Conzelmann, E., Sandhoff, K. (1986). Concepts of Ganglioside Metabolism. In: Tettamanti, G., Ledeen, R.W., Sandhoff, K., Nagai, Y., Toffano, G. (eds) Gangliosides and Neuronal Plasticity. FIDIA Research Series, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-5309-7_15
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DOI: https://doi.org/10.1007/978-1-4757-5309-7_15
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