A Tapered Fluidized Bed as a Bioreactor

  • C. D. Scott
  • C. W. Hancher
  • S. E. ShumateII

Abstract

Bioreactor systems utilizing fluidized bed techniques to contact immobilized biological fractions with liquid streams have recently been under development [e.g., (1,2)]. Such technology offers several advantages over fixed-bed systems including: (a) utilization of small particulates with high specific surface area, thus allowing greater specific reaction rates; and (b) use of particulates in a state which allows easy replacement of the active fractions even during operation -- for example, a periodic partial replenishment of the fluidized bed to maintain high reactivity.

Keywords

Void Fraction Total Pressure Drop Entry Cross Section Void Fraction Profile Chemical Technology Division 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    CHARLES, M., COUGHLIN, R.W., ALLEN, B.R., PARUCHURI, E.K. & HASSELBERGER, F.X. In “Immobilized Biochemicals and Affinity Chromatography” (Ed. R.B. Dunlap) Plenum Press, New York, 1974. p. 213.CrossRefGoogle Scholar
  2. 2.
    HASSELBERGER, F.X., ALLEN, B.R., PARUCHURI, E.K., CHARLES, M. & COUGHLIN, R.W. Biochem. Biophys. Res. Commun. 57: 1054, 1974.CrossRefGoogle Scholar
  3. 3.
    WEN, C.Y. & YU, Y.H. Chem. Eng. Progr. Symp. Ser. 62: 101, 1966.Google Scholar
  4. 4.
    KUNII, D. & LEVENSPIEL, 0. Fluidization Engineering J. Wiley, New York, 1969. p. 72.Google Scholar

Copyright information

© Springer Science+Business Media New York 1978

Authors and Affiliations

  • C. D. Scott
    • 1
  • C. W. Hancher
    • 1
  • S. E. ShumateII
    • 1
  1. 1.Chemical Technology DivisionOak Ridge National LaboratoryOak RidgeUSA

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