Endotoxin pp 417-425 | Cite as

LPS-Mediated Triggering of T Lymphocytes in Immune Response Against Gram-Negative Bacteria

  • E. Jirillo
  • C. De Simone
  • V. Covelli
  • H. Kiyono
  • J. R. McGhee
  • S. Antonaci
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 256)


Penetration of pathogens into a susceptible host triggers an array of immune responses which involve all the immunocompetent cells (T and B lymphocytes, phagocytes and Natural Killer (NK) cells). However, in the case of bacteria, phagocytosis seems to be the most effective function in order to neutralize invading organisms. At the same time, until recently the role of lymphocytes in “processing” entire bacteria has been poorly investigated, even if bacterial components are able to activate lymphocytes (21).


Antibacterial Activity Lymphoid Cell Typhoid Fever Bacterial Adherence Splenic Lymphocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • E. Jirillo
    • 1
  • C. De Simone
    • 2
  • V. Covelli
    • 3
  • H. Kiyono
    • 4
  • J. R. McGhee
    • 5
  • S. Antonaci
    • 6
  1. 1.ImmunologiaUniversity of Bari Medical SchoolBariItaly
  2. 2.Malattie InfettiveUniversity of dell’Aquila degli Abruzzi Medical SchoolL’AquilaItaly
  3. 3.Neuroanatomia ClinicaUniversity of Bari Medical SchoolBariItaly
  4. 4.Departments of Oral Biology and Preventive DentistryUniversity of Alabama at BirminghamBirminghamUSA
  5. 5.Departments of MicrobiologyUniversity of Alabama at BirminghamBirminghamUSA
  6. 6.Fisiopatologia MedicaUniversity of Bari Medical SchoolBariItaly

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