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Natural Variants of Lipid A

  • Chapter
Endotoxin

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 256))

Abstract

Recent studies by several groups (46,58,61,63) have revealed that the now “classical” structure of enterobacterial lipid A, the 1,4’-bisphosphorylated β-1,6-linked glucosamine disaccharide with amide- and esterlinked 3-hydroxy fatty acids or 3-acyloxyacyl residues (25a,44), is not universally distributed amongst gram-negative bacteria. It is especially not frequently encountered in families being phylogenetically remote from Enterobacteriaceae, such as the phototrophic bacteria or the thiobacilli. (59,65).

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Authors and Affiliations

  1. Max-Planck-Institut für Immunbiologie, D-7800, Freiburg i.Br., Germany

    H. Mayer, J. H. Krauss & A. Yokota

  2. Institut für Biologie II, Mikrobiologie, der Universität, D-7800, Freiburg i.Br., Germany

    J. Weckesser

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  1. H. Mayer
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  2. J. H. Krauss
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  1. The University of South Florida, Tampa, Florida, USA

    Herman Friedman  & T. W. Klein  & 

  2. Jichi Medical School, Tochigi-Ken, Japan

    Masayasu Nakano

  3. University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Alois Nowotny

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Mayer, H., Krauss, J.H., Yokota, A., Weckesser, J. (1990). Natural Variants of Lipid A. In: Friedman, H., Klein, T.W., Nakano, M., Nowotny, A. (eds) Endotoxin. Advances in Experimental Medicine and Biology, vol 256. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5140-6_3

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