Evolution and Mutation of the Amino Acid Code

  • J. Tze-Fei Wong
Part of the Nato Science Series A: (closed) book series (NSSA, volume 81)


The function of a protein is determined by the nature and sequence of its amino acid sidechains. Evolution of proteins must depend first of all upon development of a system of genetically encoded amino acids, and secondly upon optimization of their primary sequences. Yet, in contrast to the extensive examination of evolution of protein sequences, the mechanisms by which the system of proteinous amino acids had arrived at the present ensemble have received only limited analysis. These mechanisms are the subject of this study.


Genetic Code Encode Amino Acid Product Amino Acid Amino Acid Code Prebiotic Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • J. Tze-Fei Wong
    • 1
  1. 1.Department of BiochemistryUniversity of TorontoTorontoCanada

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