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Coping with Uncertainty: What Would an Animal Model of Schizophrenia Look Like?

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Contemporary Issues in Modeling Psychopathology

Part of the book series: Neurobiological Foundation of Aberrant Behaviors ((NFAB,volume 1))

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Abstract

In our field, where the clinical, genetic, psychophysiological, biochemical and psychopharmacological characterization of “schizophrenia” is incomplete, there has been limited success in investigating schizophrenia with the help of animal models. Nevertheless, there have been a number of putative models proposed to address individual features of the disorder. Below we review some of the models that have been suggested as being applicable to schizophrenia, outline some of the critical features required for successfully modeling schizophrenia-like behavioral features, and propose an empirically useful model of neurodevelopment and behavioral teratogenesis.

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Authors
  1. Loring J. Ingraham
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  2. Michael Myslobodsky
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Editors and Affiliations

  1. Psychobiology Research Unit, Department of Psychology, Tel Aviv University, 69978, Tel-Aviv, Israel

    Michael S. Myslobodsky

  2. Howard University, USA

    Michael S. Myslobodsky

  3. Department of Psychology, Tel Aviv University, 69978, Tel-Aviv, Israel

    Ina Weiner

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Ingraham, L.J., Myslobodsky, M. (2000). Coping with Uncertainty: What Would an Animal Model of Schizophrenia Look Like?. In: Myslobodsky, M.S., Weiner, I. (eds) Contemporary Issues in Modeling Psychopathology. Neurobiological Foundation of Aberrant Behaviors, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4860-4_16

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  • DOI: https://doi.org/10.1007/978-1-4757-4860-4_16

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