Hemodynamic Model for Determination of Asymmetric Flow

  • W. J. DorsonJr.
  • J. Marks
  • D. Hunkar
Conference paper


The application of engineering principles and in vitro (outside the body) research with biological fluids is becoming increasingly important in the design of prosthetic and diagnostic devices. One area of medicine where both theoretical and experimental studies are needed is the flow of blood in the human body. Blood is a suspension of red cells in an ionic solution containing proteins and organic compounds. The flowing blood carries nutrients to the organs and removes waste material. The red cells are distensible, and the flow of blood is non-Newtonian and has a yield stress at zero flow. Measurement of the flow rate and vascular volumes in specific areas of the human body are important for several reasons. Flow deficiency through major arteries is symptomatic of a diseased state, including major stroke, heart failure, arteriosclerosis, and senility syndromes. The exact mechanism of nutrient transfer in the capillary beds is unknown in terms of the relative contribution of mass and electrochemical transport. Such studies require an accurate measurement of regional blood flow and composition changes.


Carotid Artery Shear Rate Entrance Length Asymmetric Flow Flow Difference 
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Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • W. J. DorsonJr.
    • 1
  • J. Marks
    • 2
  • D. Hunkar
    • 3
  1. 1.Arizona State UniversityTempeUSA
  2. 2.Grant HospitalColumbusUSA
  3. 3.University of CincinnatiCincinnatiUSA

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