Abstract
A technique for investigating the diffusion properties of an artificial biological membrane, protein-lipid-protein, under static and dynamic conditions is discussed. Experimental data on the relative permeability of the membrane to manganous chloride, potassium chloride, sodium chloride, and ammonia in aqueous solutions are presented. The results indicate that manganous chloride and ammonium hydroxide diffuse through the membrane more rapidly than potassium chloride or sodium chloride, while the latter two species exhibit approximately the same overall mass transfer coefficients. It reveals the fact that such an artificial membrane is offering a degree of preferential selectivity which seems to be dependent on the electrical properties rather than on the molecular transfer coefficient of the diffusant. This characteristic is found in conformity with that of natural biological membranes.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Chargaff, E., “Lipoproteins”, in “Advances in Protein Chemistry”, Anson, M.L. and Edsall, J.T. (editors), Academic Press, Inc., New York, 1944
Danielli, J.F., Journal of Cell. and Comp. Physiology, 7, 393–400, 1935–1936
Delancey, G.B., M.S. Thesis, University of Pittsburgh, 1966
Engstrom, A., and Finean, J.B., “Biological Ultrastructure”, Academic Press, New York 1958
Hawrowitz, F., “The Chemistry and Function of Proteins”, Academic Press, New York, 1963
International Critical Tables, Vol. 5
Kavanau, J. Lee, “Structure and Function in Biological Membranes”, Vol. I, Holden-Day, Inc., San Francisco, 1965
Loewy, A.G., and Siekevitz, P., “Cell Structure and Function”, Hoff, Rinehart, and Winston, Inc., New York, 1963
Mercer, E.H., “Cells: Their Structure and Function”, The Natural History Library, Anchor Books, Doubleday and Company, Inc., Garden City, New York, 1962
Morrison, R.T., and Boyd, R.N., “Organic Chemistry”, Allyn and Bacon, Boston, 1960
Park, C.R., “General Aspects Of Transport Phenomena”, in “Membrane Transport and Metabolism”, Kleinzeller, A., and Kotyk, A. (editors), Academia Press, New York, 1960
Paul, J., “Cell Biology: A Currant Summary”, Stanford University Press, Stanford, California, 1964
Ponder, E., “Cell Membrane and Its Properties”, in “The Cell”, Brachet, J. and Mivsky, A.E. (editors) Vol. II, Academic Press, New York, 1961
Stana, R. R., M. S. Thesis, University of Pittsburgh, 1965.
Whittam, R., “The Interdependence of Metabolism and Active Transport”, in “The Cellular Functions of Membrane Transport”, Hoffman, J.F. (editor), Prentice-Hall, Inc., New Jersey, 1964
Wittcoff, H., “The Phosphatides”, American Chemical Society Monograph Service, Reinhold Publishing Corp., New York, 1951
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1967 Springer Science+Business Media New York
About this paper
Cite this paper
Delancey, G.B., Stana, R.R., Chiang, S.H. (1967). A Technique for Producing an Artificial Biological Membrane Suitable for Diffusion Studies. In: Hershey, D. (eds) Chemical Engineering in Medicine and Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4748-5_11
Download citation
DOI: https://doi.org/10.1007/978-1-4757-4748-5_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-4750-8
Online ISBN: 978-1-4757-4748-5
eBook Packages: Springer Book Archive